BDBM50134030 9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyrrolodinopropionamido) acridine::CHEMBL336434::N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3,6-diyl)bis(3-pyrrolidin-1-ylpropanamide)
SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1
InChI Key InChIKey=RKPYSYRMIXRZJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50134030
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human telomerase assessed as unincorporated [alpha32P]dGTPMore data for this Ligand-Target Pair
TargetProtection of telomeres protein 1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human 35S-labeled Pot1 binding to human telomeric DNAMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human telomerase in A549 cells by TRAP assayMore data for this Ligand-Target Pair