BDBM50182587 5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methoxybenzofuran::CHEMBL382154

SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12

InChI Key InChIKey=DPURAGOSIHFKPV-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50182587   

TargetPotassium voltage-gated channel subfamily A member 1(Homo sapiens (Human))
Institute Of Medical Research Biotechnology Centre

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effect on blockade of Kv1.1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
Institute Of Medical Research Biotechnology Centre

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  4.80E+3nMAssay Description:Effect on blockade of Kv1.4 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Institute Of Medical Research Biotechnology Centre

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  700nMAssay Description:Effect on blockade of Kv1.5 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Medical Research Biotechnology Centre

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on blockade of Kv11.1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 2(Homo sapiens (Human))
Institute Of Medical Research Biotechnology Centre

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effect on blockade of Kv1.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Mus musculus)
Institute Of Medical Research Biotechnology Centre

Curated by ChEMBL
LigandPNGBDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  480nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed