BDBM50398447 Aromasin::EXEMESTANE

SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C

InChI Key InChIKey=BFYIZQONLCFLEV-UHFFFAOYSA-N

Data  5 KI  12 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398447   

TargetAromatase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of human aromatase extracted from placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAromatase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataKi:  26nMAssay Description:Irreversible inhibition of human aromatase extracted from placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAromatase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50: 230nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)