BDBM50438865 2,4-Dioxo-10-phenyl-pyrimido[4,5-b]quinoline-8-carbonitrile (3)::CHEMBL2420506

SMILES O=c1nc2n(-c3ccccc3)c3cc(ccc3cc2c(=O)[nH]1)C#N

InChI Key InChIKey=KJCUSTLTHCEPIZ-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438865   

TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50438865(2,4-Dioxo-10-phenyl-pyrimido[4,5-b]quinoline-8-car...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of N-terminal His-tagged human TDP2 expressed in Escherichia coli BL21 using 4-nitrophenyl phenylphosphonate as substrate incubated for 60...More data for this Ligand-Target Pair
In DepthDetails PubMed