Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with Target = 'Dihydropteroate synthase'
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031525BDBM50031525(CHEMBL3233211)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190582BDBM50190582(CHEMBL3827911)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190581BDBM50190581(CHEMBL3828161)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190578BDBM50190578(CHEMBL3827297)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031522BDBM50031522(CHEMBL3233207)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031523BDBM50031523(CHEMBL3233201)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378554BDBM50378554(CHEMBL577547)
Affinity DataKd:  5.26E+3nMAssay Description:Binding affinity to Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145829BDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataKd:  5.62E+3nMAssay Description:Binding affinity to Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031528BDBM50031528(CHEMBL3359160)
Affinity DataKd:  7.80E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378552BDBM50378552(CHEMBL291324)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190579BDBM50190579(CHEMBL3828532)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031524BDBM50031524(CHEMBL3233212)
Affinity DataKd:  8.20E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031526BDBM50031526(CHEMBL3359158)
Affinity DataKd:  8.40E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031531BDBM50031531(CHEMBL3359162)
Affinity DataKd:  8.50E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190580BDBM50190580(CHEMBL3828019)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031532BDBM50031532(CHEMBL3359163)
Affinity DataKd:  9.74E+3nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190584BDBM50190584(CHEMBL3828105)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190583BDBM50190583(CHEMBL3827459)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031533BDBM50031533(CHEMBL3233202)
Affinity DataKd:  1.23E+4nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031527BDBM50031527(CHEMBL3359159)
Affinity DataKd:  1.42E+4nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190583BDBM50190583(CHEMBL3827459)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190585BDBM50190585(CHEMBL3828540)
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190584BDBM50190584(CHEMBL3828105)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190585BDBM50190585(CHEMBL3828540)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378553BDBM50378553(CHEMBL161604)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190580BDBM50190580(CHEMBL3828019)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378551BDBM50378551(CHEMBL568630)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190578BDBM50190578(CHEMBL3827297)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190579BDBM50190579(CHEMBL3828532)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378560BDBM50378560(CHEMBL566065)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190582BDBM50190582(CHEMBL3827911)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378554BDBM50378554(CHEMBL577547)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031529BDBM50031529(CHEMBL3359161)
Affinity DataKd:  4.39E+4nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190581BDBM50190581(CHEMBL3828161)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Escherichia coli (strain K12))
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108009BDBM50108009(2-Amino-8-mercapto-1,9-dihydro-purin-6-one | 2-ami...)
Affinity DataKd:  7.62E+4nMAssay Description:Binding affinity to Escherichia coli DHPS by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378557BDBM50378557(CHEMBL577755)
Affinity DataIC50: 8.67E+4nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378561BDBM50378561(CHEMBL576455)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378555BDBM50378555(CHEMBL571066)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378559BDBM50378559(CHEMBL344471)
Affinity DataIC50: 2.13E+5nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378558BDBM50378558(CHEMBL578135)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378562BDBM50378562(CHEMBL567987)
Affinity DataIC50: 2.69E+5nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378556BDBM50378556(CHEMBL566922)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed