Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase HST2'
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304357BDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataKi:  1.20E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178766BDBM50178766(2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304355BDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataKi:  2.50E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304355BDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataKi:  2.50E+3nMAssay Description:Mixed inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242434BDBM50242434((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242443BDBM50242443(butyryl-lysine peptide | [amino({[(5S)-5-{[(2S)-1-...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242442BDBM50242442((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242440BDBM50242440((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242439BDBM50242439((1-{[(5S)-5-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-5-ami...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242438BDBM50242438((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242436BDBM50242436((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242435BDBM50242435((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304357BDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataKi:  6.30E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304357BDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242437BDBM50242437((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  8.60E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304355BDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304356BDBM50304356(2-methyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242441BDBM50242441((2S)-2-[(2S)-6-amino-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(...)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304354BDBM50304354(cid_648461 | CHEMBL82949 | 3-(1-Oxo-1,3-dihydro-is...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304354BDBM50304354(cid_648461 | CHEMBL82949 | 3-(1-Oxo-1,3-dihydro-is...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3175BDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242433BDBM50242433((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304354BDBM50304354(cid_648461 | CHEMBL82949 | 3-(1-Oxo-1,3-dihydro-is...)
Affinity DataKi:  3.00E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304354BDBM50304354(cid_648461 | CHEMBL82949 | 3-(1-Oxo-1,3-dihydro-is...)
Affinity DataKi:  3.90E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304351BDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataKi:  4.20E+4nMAssay Description:Mixed inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304351BDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataKi:  4.30E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156760BDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27507BDBM27507(pyridine-3-carboxamide | nicotinamide | 3-Pyridine...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 99917BDBM99917(4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)ph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304351BDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336799BDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304352BDBM50304352(6-methoxy-2-(4-methoxy-benzyl)-1-(3-methoxy-prop-1...)
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29590BDBM29590(1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378583BDBM50378583(SURFACTIN)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase HST2(Baker's yeast)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29040BDBM29040(cambinol)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed