Compile Data Set for Download or QSAR
Report error Found 594 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 2'
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358558BDBM50358558(CHEMBL1923557)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552141BDBM50552141(CHEMBL4756806)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526708BDBM50526708(CHEMBL4552043)
Affinity DataEC50:  0.281nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552143BDBM50552143(CHEMBL4759425)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526714BDBM50526714(CHEMBL4442356)
Affinity DataEC50:  0.304nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552142BDBM50552142(CHEMBL4791879)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526709BDBM50526709(CHEMBL4546202)
Affinity DataEC50:  0.383nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358537BDBM50358537(CHEMBL1923536)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526710BDBM50526710(CHEMBL4560927)
Affinity DataEC50:  0.468nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552140BDBM50552140(CHEMBL4780449)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358542BDBM50358542(CHEMBL1923541)
Affinity DataEC50:  0.560nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600865BDBM50600865(CHEMBL5205616)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526713BDBM50526713(CHEMBL4461230)
Affinity DataEC50:  0.609nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600930BDBM50600930(CHEMBL5191001)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600917BDBM50600917(CHEMBL5195088)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600890BDBM50600890(CHEMBL5196750)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600880BDBM50600880(CHEMBL5181631)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600888BDBM50600888(CHEMBL5179644)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600896BDBM50600896(CHEMBL5183964)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358539BDBM50358539(CHEMBL1923538)
Affinity DataEC50:  0.870nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600870BDBM50600870(CHEMBL5181859)
Affinity DataEC50:  1nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358538BDBM50358538(CHEMBL1923537)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50386534BDBM50386534(CHEMBL2048075 | US9676818, 11d)
Affinity DataEC50:  1.01nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600938BDBM50600938(CHEMBL5192641)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526719BDBM50526719(CHEMBL4537583)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600852BDBM50600852(CHEMBL5199615)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600864BDBM50600864(CHEMBL5179849)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511993BDBM50511993(CHEMBL4472879)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600848BDBM50600848(CHEMBL5190772)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358543BDBM50358543(CHEMBL1923542)
Affinity DataEC50:  1.47nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600877BDBM50600877(CHEMBL5203424)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358546BDBM50358546(CHEMBL1923545)
Affinity DataEC50:  1.55nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50386538BDBM50386538(CHEMBL2048076 | US9676818, 11e)
Affinity DataEC50:  1.64nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600894BDBM50600894(CHEMBL5169958)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358549BDBM50358549(CHEMBL1923548)
Affinity DataEC50:  1.86nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358548BDBM50358548(CHEMBL1923547)
Affinity DataEC50:  1.95nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600897BDBM50600897(CHEMBL5184916)
Affinity DataEC50:  2nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600937BDBM50600937(CHEMBL5169846)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600921BDBM50600921(CHEMBL5191273)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358545BDBM50358545(CHEMBL1923544)
Affinity DataEC50:  2.11nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600915BDBM50600915(CHEMBL5206742)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600871BDBM50600871(CHEMBL5201759)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600939BDBM50600939(CHEMBL5170841)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600862BDBM50600862(CHEMBL5172228)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358547BDBM50358547(CHEMBL1923546)
Affinity DataEC50:  3.23nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600882BDBM50600882(CHEMBL5180856)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600900BDBM50600900(CHEMBL5198565)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600886BDBM50600886(CHEMBL5203059)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at TLR1/TLR2 in wild type C57BL/6J mouse macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358550BDBM50358550(CHEMBL1923549 | US9676818, 6d)
Affinity DataEC50:  3.63nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399457BDBM50399457(CHEMBL2179400)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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