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Found 25 with Last Name = 'binder' and Initial = 'd'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  0.940nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473905(CHEMBL130814)
Affinity DataKi:  1.89nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473905(CHEMBL130814)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473904(CHEMBL2112670)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473907(CHEMBL2112671)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473906(CHEMBL2111861)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473910(CHEMBL2111860)
Affinity DataKi:  533nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473908(CHEMBL2112676)
Affinity DataKi:  962nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473903(CHEMBL335828)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473903(CHEMBL335828)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Vienna University of Technology

Curated by ChEMBL
LigandPNGBDBM50473909(CHEMBL2111859)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataIC50:  4nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602485(CHEMBL5171919)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  49nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataIC50:  110nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602485(CHEMBL5171919)
Affinity DataIC50:  120nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  150nMAssay Description:Inhibition of Tyro3 (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataIC50:  170nMAssay Description:Inhibition of Axl (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602485(CHEMBL5171919)
Affinity DataIC50:  200nMAssay Description:Inhibition of Axl (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  218nMAssay Description:Inhibition of Axl (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary ele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602485(CHEMBL5171919)
Affinity DataIC50:  390nMAssay Description:Inhibition of Tyro3 (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataIC50:  400nMAssay Description:Inhibition of Tyro3 (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataKd:  13nMAssay Description:Binding affinity to MERTK in cuprizone-challenged C57BL/6 mouse whole brain assessed as dissociation constant at 18.1 nM by autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataKd:  20nMAssay Description:Binding affinity to MERTK in cuprizone-challenged C57BL/6 mouse brain CC/HC region assessed as dissociation constant at 18.1 nM by autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed