Affinity DataIC50: 2.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg
Curated by ChEMBL
UniversitäT Regensburg
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg
Curated by ChEMBL
UniversitäT Regensburg
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center
Curated by ChEMBL
National Defense Medical Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
UniversitäT Regensburg
Curated by ChEMBL
UniversitäT Regensburg
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Tested for inhibition of 12-LO (12-lipoxygenase) as an inhibitor of 12(S)-HETE biosynthesis in mouse epidermal homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center
Curated by ChEMBL
National Defense Medical Center
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center
Curated by ChEMBL
National Defense Medical Center
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center
Curated by ChEMBL
National Defense Medical Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 alpha assessed as blocking of supercoiled pHOT DNA relaxation incubated for 45 mins at 37 degC by eth...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant topoisomerase 1 assessed as blocking of supercoiled pHOT DNA relaxation incubated for 25 mins at 37 degC by ethidium ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Defense Medical Center
Curated by ChEMBL
National Defense Medical Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNLMore data for this Ligand-Target Pair