Affinity DataIC50: 0.170nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of intact cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibitory concentration against adenosine kinase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against intact cell adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of intact cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition adenosine kinase activity in rat brain in vitroMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as capsaicin-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.12nMAssay Description:In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair