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Found 277 with Last Name = 'payne' and Initial = 'rj'
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602543(CHEMBL4598338)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Mus musculus)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataKi:  4nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Mus musculus)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataKi:  4.20nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Mus musculus)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataKi:  5.30nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataKi:  11.8nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Mus musculus)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602543(CHEMBL4598338)
Affinity DataKi:  16.5nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Mus musculus)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataKi:  29.3nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataKi:  117nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataKi:  238nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602543(CHEMBL4598338)
Affinity DataKi:  347nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataKi:  853nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataKi:  861nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSalicylate synthase(Mycobacterium tuberculosis)
The University of Auckland

LigandPNGBDBM92747(cyclopropyl-AMT)
Affinity DataKi:  1.20E+4nMAssay Description:The thermal stability of MbtI in the absence and presence of inhibitors was measured using a fluorescence-based thermal shift assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602543(CHEMBL4598338)
Affinity DataIC50:  0.00600nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataIC50:  0.00600nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataIC50:  0.00900nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of human recombinant Cathepsin S assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataIC50:  0.0170nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  0.0180nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603782(CHEMBL4596414)
Affinity DataIC50:  0.0810nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataIC50:  0.0860nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603779(CHEMBL3558756)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603794(CHEMBL5184737)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603788(CHEMBL5171874)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603795(CHEMBL5175270)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataIC50:  0.149nMAssay Description:Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602545(CHEMBL4596647)
Affinity DataIC50:  0.224nMAssay Description:Inhibition of human recombinant Cathepsin S assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603793(CHEMBL5199542)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataIC50:  0.278nMAssay Description:Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603792(CHEMBL5176188)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataIC50:  0.304nMAssay Description:Inhibition of human recombinant Cathepsin S assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603781(CHEMBL4596941)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  0.367nMAssay Description:Inhibition of human recombinant Cathepsin S assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603789(CHEMBL5183942)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602544(CHEMBL4594757)
Affinity DataIC50:  0.416nMAssay Description:Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603783(CHEMBL4595806)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin K(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50602542(CHEMBL4594870)
Affinity DataIC50:  0.623nMAssay Description:Inhibition of human recombinant Cathepsin K assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603790(CHEMBL5191563)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603796(CHEMBL5204190)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603787(CHEMBL4597308)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603780(CHEMBL4596992)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603791(CHEMBL5179302)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50603786(CHEMBL4595664)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50602543(CHEMBL4598338)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
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