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Found 96 with Last Name = 'chitturi' and Initial = 'tr'
LigandPNGBDBM50405810(CHEMBL5284610)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355462(CHEMBL1835559)
Affinity DataIC50:  70nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405814(CHEMBL5285899)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355463(CHEMBL1835560)
Affinity DataIC50:  74nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355458(CHEMBL1835555)
Affinity DataIC50:  80nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405806(CHEMBL5275653)
Affinity DataIC50:  80nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405807(CHEMBL5287773)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405805(CHEMBL5289840)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405803(CHEMBL5284469)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405802(CHEMBL5278951)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405801(CHEMBL5289950)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405811(CHEMBL5277536)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355460(CHEMBL1835557)
Affinity DataIC50:  126nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM26806((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...)
Affinity DataIC50:  130nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405804(CHEMBL5279230)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405808(CHEMBL5279096)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405813(CHEMBL5288731)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405818(CHEMBL5273550)
Affinity DataIC50:  140nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405811(CHEMBL5277536)
Affinity DataIC50:  150nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50177180(3-(4-(4-hydroxyphenyl)piperazin-1-yl)-1-phenylpyrr...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405808(CHEMBL5279096)
Affinity DataIC50:  150nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405808(CHEMBL5279096)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405817(CHEMBL5267542)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405824(CHEMBL5279589)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355459(CHEMBL1835556)
Affinity DataIC50:  160nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405806(CHEMBL5275653)
Affinity DataIC50:  170nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405803(CHEMBL5284469)
Affinity DataIC50:  180nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405807(CHEMBL5287773)
Affinity DataIC50:  180nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405803(CHEMBL5284469)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405815(CHEMBL5278596)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405802(CHEMBL5278951)
Affinity DataIC50:  200nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50177180(3-(4-(4-hydroxyphenyl)piperazin-1-yl)-1-phenylpyrr...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405800(CHEMBL5267207)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405807(CHEMBL5287773)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405809(CHEMBL5283020)
Affinity DataIC50:  210nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405800(CHEMBL5267207)
Affinity DataIC50:  220nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50177180(3-(4-(4-hydroxyphenyl)piperazin-1-yl)-1-phenylpyrr...)
Affinity DataIC50:  220nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405802(CHEMBL5278951)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405806(CHEMBL5275653)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405812(CHEMBL5281297)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405825(CHEMBL5286488)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405826(CHEMBL5290463)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405805(CHEMBL5289840)
Affinity DataIC50:  270nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405805(CHEMBL5289840)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405811(CHEMBL5277536)
Affinity DataIC50:  270nMAssay Description:In vitro inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355461(CHEMBL1835558)
Affinity DataIC50:  280nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50405822(CHEMBL5274945)
Affinity DataIC50:  310nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405809(CHEMBL5283020)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50405801(CHEMBL5289950)
Affinity DataIC50:  340nMAssay Description:50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50405810(CHEMBL5284610)
Affinity DataIC50:  350nMAssay Description:In vitro inhibition of human Carbonic Anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails PubMed
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