Affinity DataKi: 0.100nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at human PAR1 in HCASMC assessed as inhibition of thrombin-induced calcium effluxMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 2nM ΔG°: -50.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 3.80nM ΔG°: -48.9kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to human B1 bradykinin receptorMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]haTRAP from PAR-1 isolated from human platelets by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]haTRAP from PAR-1 receptor in human platelet membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 8nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of high affinity TRAP form human platelet PAR1More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]haTRAP from PAR-1 isolated from human platelets by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Displacement of [3H]haTRAP from PAR-1 isolated from human platelets by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Displacement of [3H]haTRAP from PAR-1 receptor in human platelet membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair