TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Istituto Di Chimica Biomolecolare (Icb)
Curated by ChEMBL
Istituto Di Chimica Biomolecolare (Icb)
Curated by ChEMBL
Affinity DataKi: 0.000590nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Istituto Di Chimica Biomolecolare (Icb)
Curated by ChEMBL
Istituto Di Chimica Biomolecolare (Icb)
Curated by ChEMBL
Affinity DataKi: 0.0585nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Inhibition of human P2Y14RMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Istituto Di Chimica Biomolecolare (Icb)
Curated by ChEMBL
Istituto Di Chimica Biomolecolare (Icb)
Curated by ChEMBL
Affinity DataKi: 0.221nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 14(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Antagonist activity at P2Y14R in rat C6 cells assessed as suppression of UDP-glucose-mediated inhibition of forskolin-stimulated [3H]cyclic-AMP accum...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant MMP-1 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of MMP-13 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition of MMP-8 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to FAP (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of MMP-2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 19nM ΔG°: -44.1kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -43.8kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 23nM ΔG°: -43.6kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.5kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 27nMpH: 5.9Assay Description:Inhibition of bovine pancreatic RNase A at pH 5.9 by spectrophotometric methodMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]Rauwolscine from human adrenergic alpha2A receptor expressed in MDCK cell membranes after 90 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant MMP-1 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Competitive inhibition of Escherichia coli DHFR by Lineweaver-Burk plot analysis in presence of H2FMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human recombinant MMP-3 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 45nM ΔG°: -41.9kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of Escherichia coli DHFR assessed as NADP formation by quadratic Morrison plot analysisMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Inhibition of MMP-9 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda
Curated by ChEMBL
The M. S. University Of Baroda
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Inhibition of Escherichia coli DHFR assessed as NADP formation by quadratic Morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 101nMAssay Description:Competitive inhibition of Escherichia coli DHFR by Lineweaver-Burk plot analysis in presence of H2FMore data for this Ligand-Target Pair
Affinity DataKi: 112nM ΔG°: -39.7kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
Affinity DataKi: 134nMAssay Description:Inhibition of MMP-3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair