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Found 209 with Last Name = 'david-pierson' and Initial = 'p'
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86998((2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,3]...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87007((2-(2,4-dichlorophenyl)-6-fluoro-2-(4-methoxypheny...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86984((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86989(1-(2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86984((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86984((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86995((2-(2,4-dichlorophenyl)-6-fluoro-2-(2-fluorophenyl...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87003((2-(2,4-dichlorophenyl)-6-fluoro-2-(4-fluorophenyl...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86997((6-fluoro-2,2-bis(4-fluorophenyl)benzo[d][1,3]diox...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86992((2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,3]...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87009(4-(2-(2,4-dichlorophenyl)-6-fluoro-2-(4-fluorophen...)
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86986((6-fluoro-2,2-diphenylbenzo[d][1,3]dioxol-5-yl)(pi...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87000(1-(2,2-diphenyl-benzo[1,3]dioxole-5-sulfonyl)-4-(4...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86999((2,2-diphenyl-[1,3]dioxolo[4,5-c]pyridin-6-yl)-pip...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86993((6-fluoro-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-morp...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87006((6-fluoro-2,2-bis(4-fluorophenyl)benzo[d][1,3]diox...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87012(4-(2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][1,...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86991((2,2-diphenylbenzo[d][1,3]dioxol-5-yl)(piperidin-1...)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87001((2-(2,4-dichlorophenyl)-2-(4-fluorophenyl)benzo[d]...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86984((R)-[2-(2,4-dichloro-phenyl)-6-fluoro-2-(4-fluoro-...)
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87004(1-(2,2-diphenyl-benzo[1,3]dioxole-5-sulfonyl)-pipe...)
Affinity DataKi:  38nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87011((S)-(2,2-bis(2,4-difluorophenyl)-6-fluorobenzo[d][...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87008((2,2-diphenylbenzo[d][1,3]dioxol-5-yl)(morpholino)...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87005((6-(methylsulfonyl)-1-pentyl-1H-indol-3-yl)(naphth...)
Affinity DataKi:  110nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86988((6-chloro-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-morp...)
Affinity DataKi:  216nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86990(6-(morpholine-4-carbonyl)-2,2-diphenyl-benzo[1,3]d...)
Affinity DataKi:  277nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86994((6-methyl-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-morp...)
Affinity DataKi:  509nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86985((6-bromo-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-morph...)
Affinity DataKi:  873nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM86996(4-[6-fluoro-2,2-bis-(4-fluoro-phenyl)-benzo[1,3]di...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87010(1-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM87000(1-(2,2-diphenyl-benzo[1,3]dioxole-5-sulfonyl)-4-(4...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477148(CHEMBL235870)
Affinity DataIC50:  0.00200nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477143(CHEMBL392113)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477136(CHEMBL235659)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477131(CHEMBL235869)
Affinity DataIC50:  0.0240nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477131(CHEMBL235869)
Affinity DataIC50:  0.0370nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477136(CHEMBL235659)
Affinity DataIC50:  0.0420nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477143(CHEMBL392113)
Affinity DataIC50:  0.0750nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477134(CHEMBL393542)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477134(CHEMBL393542)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50432608(CHEMBL2347204 | US8754075, 4)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50432632(CHEMBL2347211)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50432615(CHEMBL2347197)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50432614(CHEMBL2347198)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477145(CHEMBL235648)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477146(CHEMBL428374)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50477142(CHEMBL235226)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478057(CHEMBL256059)
Affinity DataIC50:  2nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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