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Found 30 with Last Name = 'grosdemange-billiard' and Initial = 'c'
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataKi:  7.70E+3nMAssay Description:Uncompetitive inhibition of His-tagged Escherichia coli DXR at 1 to 8 uM pre-incubated for 2 mins before reaction initiation in presence of 160 uM NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  32nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  42nMpH: 7.5Assay Description:Assays were performed in 50 mM Tris/HCl buffer, pH 7.5, containing 3 mM MgCl2 and 2 mM DTT. The concentrations of NADPH and DXP were 0.15 and 0.5 mM ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Mycobacterium smegmatis DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataIC50:  400nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)
Affinity DataIC50:  410nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044967(CHEMBL3309759)
Affinity DataIC50:  500nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)
Affinity DataIC50:  510nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044973(CHEMBL3309761)
Affinity DataIC50:  700nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044971(CHEMBL3309760)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044974(CHEMBL3309762)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50379999(CHEMBL1161784)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  1.50E+3nMAssay Description:H-DXR was pre-incubated during 2 min in the presence of the inhibitors at different concentrations and DXP (480 µM). NADPH (160 µM final concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  1.90E+3nMAssay Description:H-DXR was pre-incubated during 2 min in the presence of the inhibitors at different concentrations and DXP (480 µM). NADPH (160 µM final concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  2.20E+3nMAssay Description:H-DXR was pre-incubated during 2 min in the presence of the inhibitors at different concentrations and DXP (480 µM). NADPH (160 µM final concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044967(CHEMBL3309759)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044973(CHEMBL3309761)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  3.40E+3nMAssay Description:H-DXR was pre-incubated during 2 min in the presence of the inhibitors at different concentrations and DXP (480 µM). NADPH (160 µM final concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044975(CHEMBL3309763)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  3.50E+3nMAssay Description:H-DXR was pre-incubated during 2 min in the presence of the inhibitors at different concentrations and DXP (480 µM). NADPH (160 µM final concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044971(CHEMBL3309760)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044975(CHEMBL3309763)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044975(CHEMBL3309763)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in presence of 0.01% Triton X100 by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044974(CHEMBL3309762)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed