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Found 41 with Last Name = 'kamionka' and Initial = 'm'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31274(Chalcone derivative, B)
Affinity DataIC50:  4.90E+4nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31275(Chalcone derivative, B-1)
Affinity DataIC50:  1.17E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31273(Chalcone derivative, A)
Affinity DataIC50:  2.06E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31279(Chalcone derivative, F)
Affinity DataIC50: >2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31278(Chalcone derivative, E)
Affinity DataIC50: >2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31280(Chalcone derivative, G)
Affinity DataIC50: >2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31277(Chalcone derivative, D)
Affinity DataIC50: >2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31276(Chalcone derivative, C)
Affinity DataIC50:  2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31281(Chalcone derivative, H)
Affinity DataIC50: >2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.64E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.42E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.78E+6nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.38E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  7.83E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121968(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methyl-p...)
Affinity DataKd:  1.09E+6nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.36E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.10E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.33E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.93E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.58E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121969(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-p...)
Affinity DataKd:  1.08E+6nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.78E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  7.19E+8nMAssay Description:Dissociation constant of the compound in BS binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.50E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.12E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  5.41E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.72E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.48E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.88E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.31E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.82E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.90E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  9.21E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121965(3-(4-tert-Butoxy-phenyl)-2-(9H-fluoren-9-ylmethoxy...)
Affinity DataKd:  7.18E+5nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31283(Chalcone derivative, N)
Affinity DataKd:  2.70E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31282(Chalcone derivative, L)
Affinity DataKd:  2.50E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31276(Chalcone derivative, C)
Affinity DataKd:  2.44E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31275(Chalcone derivative, B-1)
Affinity DataKd:  1.50E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31274(Chalcone derivative, B)
Affinity DataKd:  9.00E+4nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31273(Chalcone derivative, A)
Affinity DataKd:  2.20E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50121967(CHEMBL152301 | N-alpha-FMOC-L-tryptophan)
Affinity DataKd:  4.32E+4nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed