Affinity DataKi: 0.0940nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Dissociation constant for [3H]-DMP728 binding to alphaIIb beta III integrinMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
Affinity DataKi: 0.270nM ΔG°: -50.8kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nM ΔG°: -50.7kJ/mole EC50: 1nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity against human androgen receptor (hAR) in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -50.5kJ/mole EC50: 500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
Affinity DataKi: 0.302nMAssay Description:Binding affinity for human Beta-2 adrenergic receptor expressed in CHO cells by radioligand competition binding assays using [125I]iodocyanopindolol ...More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nM ΔG°: -49.7kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.540nM ΔG°: -49.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:In vitro binding affinity measured by displacement of [3H]rauwolscine from alpha-2c adrenergic receptor expressed in CHO cells in presence of phentol...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Tennessee-Memphis
Curated by ChEMBL
University Of Tennessee-Memphis
Curated by ChEMBL
Affinity DataKi: 0.760nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.860nM ΔG°: -48.1kJ/mole EC50: 500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:In vitro binding affinity measured by displacement of [3H]rauwolscine from alpha-2c adrenergic receptor expressed in CHO cells in presence of phentol...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:In vitro binding affinity measured by displacement of [3H]rauwolscine from alpha-2c adrenergic receptor expressed in CHO cells in presence of phentol...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Compound was tested for inhibitory activity against the binding of [3H]-spiperone to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity against human Alpha-2A adrenergic receptor expressed stably in CHO cells using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:In vitro binding affinity towards alpha-2a adrenergic receptorMore data for this Ligand-Target Pair