TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Competitive inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by Lineweaver-Burk plot analysis in presence of...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]NMS from human M1 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]NMS from human M5 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]NMS from human M2 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]NMS from human M5 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]NMS from human M1 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]NMS from human M4 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.10nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]NMS from human M1 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]NMS from human M5 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]NMS from human M2 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of human carbonic anhydrase 13 expressed in Escherichia coliBL21(DE3) pLysS incubated for 10 mins by phenol red dye based assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of [3H]NMS from human M4 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H]NMS from human M1 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair