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Found 104 with Last Name = 'liston' and Initial = 'dr'
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032162(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,7-dihydro-...)
Affinity DataIC50:  0.330nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032161(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-7-methyl-5,7...)
Affinity DataIC50:  0.480nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032164(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5,6-dihydroiso...)
Affinity DataIC50:  0.570nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039721(3-(2-(1-benzylpiperidin-4-yl)ethyl)-6-morpholinobe...)
Affinity DataIC50:  0.800nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032163(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5H-isoxazolo[5...)
Affinity DataIC50:  0.950nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032165(CHEMBL92736 | CHEMBL94217 | N-{3-[2-(1-Benzyl-pipe...)
Affinity DataIC50:  2.80nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032165(CHEMBL92736 | CHEMBL94217 | N-{3-[2-(1-Benzyl-pipe...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032160(3-(2-(1-benzylpiperidin-4-yl)ethyl)-6H-isoxazolo[5...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034001(3-(1-Benzyl-piperidin-4-yl)-1-(1-ethyl-2-methyl-1H...)
Affinity DataIC50:  4.30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039729(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5,6-dimethylbe...)
Affinity DataIC50:  5.80nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  6nMAssay Description:Compound was evaluated for the in vitro inhibition of the Butyrylcholinesterase from horse serumMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  6nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034002(3-(1-Benzyl-piperidin-4-yl)-1-(2-methyl-benzothiaz...)
Affinity DataIC50:  6.80nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039713(3-(2-(1-benzylpiperidin-4-yl)ethyl)-7-methoxybenzo...)
Affinity DataIC50:  7.10nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039712(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5-methoxybenzo...)
Affinity DataIC50:  7.20nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039728(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5-methylbenzo[...)
Affinity DataIC50:  7.80nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039717(3-(2-(1-benzylpiperidin-4-yl)ethyl)-6-methoxybenzo...)
Affinity DataIC50:  8.30nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039723(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  8.80nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039727(CHEMBL93123 | N-(3-(2-(1-benzylpiperidin-4-yl)ethy...)
Affinity DataIC50:  9.40nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034003(3-(1-Benzyl-piperidin-4-yl)-1-(2-methyl-1H-benzoim...)
Affinity DataIC50:  12nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039725(CHEMBL92955 | N-(3-(2-(1-benzylpiperidin-4-yl)ethy...)
Affinity DataIC50:  14nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  19nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  19nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039719(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  20nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039731(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  26nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034000(3-(1-Benzyl-piperidin-4-yl)-1-(2,3-dihydro-benzo[1...)
Affinity DataIC50:  30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034004(3-(1-Benzyl-piperidin-4-yl)-1-(2-phenyl-1H-benzoim...)
Affinity DataIC50:  33nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50279984(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine | 9-...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50279990(10-Amino-3,4-dihydro-2H-1-oxa-7-aza-9-azonia-anthr...)
Affinity DataIC50:  42nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039734(3-(2-(1-benzylpiperidin-4-yl)ethyl)-6-bromobenzo[d...)
Affinity DataIC50:  50nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50150885(6-(4-Dimethylaminomethyl-5-ethyl-2-methoxy-phenyl)...)
Affinity DataIC50:  54nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039716(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  55nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50150887(6-[4-(2-Dimethylamino-ethoxy)-5-ethyl-2-methoxy-ph...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  73nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  73nMAssay Description:Compound was evaluated for the in vitro inhibition of the Butyrylcholinesterase from horse serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50150890(6-[4-(2-Dimethylamino-ethyl)-5-ethyl-2-methoxy-phe...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50150884(6-[4-(3-Dimethylamino-propyl)-5-ethyl-2-methoxy-ph...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50279995(8-Fluoro-1,2,3,4-tetrahydro-acridin-9-ylamine | 9-...)
Affinity DataIC50:  78nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50279983(8-Methyl-1,2,3,4-tetrahydro-acridin-9-ylamine | CH...)
Affinity DataIC50:  99nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039715(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-benzo[d]isot...)
Affinity DataIC50:  99nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039718(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  101nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50150883(6-[4-(2-Dimethylamino-ethoxy)-2,5-dimethoxy-phenyl...)
Affinity DataIC50:  112nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039720(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-1H-indazole ...)
Affinity DataIC50:  120nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081082(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  143nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
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