Affinity DataKi: 0.0380nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.107nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.131nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.179nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.183nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alphaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alphaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alphaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alphaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor in Cos-7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.460nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Binding affinity for cloned human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Centre De Recherche Pierre Fabre
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair