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Found 62 with Last Name = 'salter' and Initial = 'r'
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  1.80nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  1.80nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  1.80nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  2nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetColony stimulating factor 1 receptor(Canis lupus familiaris (Dog) (Canis familiaris))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  2nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetColony stimulating factor 1 receptor(Canis lupus familiaris (Dog) (Canis familiaris))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2.20nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2.20nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2.20nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2.20nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2.20nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  2.20nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  2.5nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  2.5nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276745(US10071991, Compound (I-M2-2R,4S) | US10800764, Co...)
Affinity DataIC50:  2.5nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetColony stimulating factor 1 receptor(Canis lupus familiaris (Dog) (Canis familiaris))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276746(US10071991, Compound (I-M7-2S,4R) | US11214566, Co...)
Affinity DataIC50:  6.60nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM466797(US10800764, Compound (I-M7-2S,4R))
Affinity DataIC50:  6.60nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276746(US10071991, Compound (I-M7-2S,4R) | US11214566, Co...)
Affinity DataIC50:  6.60nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532954(US11214566, Compound (I-M7-2R,4S))
Affinity DataIC50:  7.10nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  7.10nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276747(US10071991, Compound (I-M7-2R,4S))
Affinity DataIC50:  7.10nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM466797(US10800764, Compound (I-M7-2S,4R))
Affinity DataIC50:  7.90nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM466797(US10800764, Compound (I-M7-2S,4R))
Affinity DataIC50:  7.90nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276746(US10071991, Compound (I-M7-2S,4R) | US11214566, Co...)
Affinity DataIC50:  7.90nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276746(US10071991, Compound (I-M7-2S,4R) | US11214566, Co...)
Affinity DataIC50:  7.90nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276746(US10071991, Compound (I-M7-2S,4R) | US11214566, Co...)
Affinity DataIC50:  7.90nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276746(US10071991, Compound (I-M7-2S,4R) | US11214566, Co...)
Affinity DataIC50:  7.90nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  8nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetColony stimulating factor 1 receptor(Canis lupus familiaris (Dog) (Canis familiaris))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276747(US10071991, Compound (I-M7-2R,4S))
Affinity DataIC50:  8nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor protein-tyrosine kinase(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532954(US11214566, Compound (I-M7-2R,4S))
Affinity DataIC50:  8nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532954(US11214566, Compound (I-M7-2R,4S))
Affinity DataIC50:  9.60nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276747(US10071991, Compound (I-M7-2R,4S))
Affinity DataIC50:  9.60nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276744(US10071991, Compound (I-M2-2S,4R) | US10800764, Co...)
Affinity DataIC50:  9.60nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM466793(US10800764, Compound (I-M7))
Affinity DataIC50:  10nMAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276742(US10071991, Compound (I-M7) | US9611259, Compound ...)
Affinity DataIC50:  10nMAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  10nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276742(US10071991, Compound (I-M7) | US9611259, Compound ...)
Affinity DataIC50:  10nMpH: 7.0 T: 2°CAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  10nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532949(US11214566, Compound (I-M7))
Affinity DataIC50:  10nMAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  10nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  11nMpH: 7.0 T: 2°CAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276741(US10071991, Compound (I-M2) | US10800764, Compound...)
Affinity DataIC50:  11nMAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276741(US10071991, Compound (I-M2) | US10800764, Compound...)
Affinity DataIC50:  11nMpH: 7.0 T: 2°CAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276741(US10071991, Compound (I-M2) | US10800764, Compound...)
Affinity DataIC50:  11nMAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276741(US10071991, Compound (I-M2) | US10800764, Compound...)
Affinity DataIC50:  11nMAssay Description:c-fms(h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  11nMAssay Description:Materials:Human c-fms protein (N-terminal 6His-tagged, amino acids 538-972), dog c-fms protein (N-terminal 6His-tagged, amino acids 535-967) and rat ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276743(US10071991, Compound (P) | US10800764, Compound (P...)
Affinity DataIC50:  11nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
In DepthDetails US Patent
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