TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain-containing protein 2 [71-194,348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain-containing protein 3 [24-144,306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain-containing protein 4 [44-168,333-460](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain-containing protein 2 [71-194,348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain testis-specific protein [251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain testis-specific protein [21-137,251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain testis-specific protein [251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain-containing protein 4 [44-168,333-460](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain-containing protein 3 [24-144,306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain testis-specific protein [21-137](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain testis-specific protein [21-137,251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
TargetBromodomain testis-specific protein [21-137](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Affinity DataKi: 0.800nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 627nMAssay Description:Displacement of [3H]furoyl-LIGRL-NH2 from human protease-activated receptor 2 in NCTC-2544 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Mixed type inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nM IC50: 4.20E+3nMpH: 8.0Assay Description:Reactions were performed in a total volume of 200 mL, which contained thefollowing components: 20mM Tris-buffer, pH 8.0, 10mM DTT, 30 mM Z-RLRGG-AMC,...More data for this Ligand-Target Pair
Affinity DataKi: 1.94E+3nMAssay Description:Displacement of [3H]furoyl-LIGRL-NH2 from human protease-activated receptor 2 in NCTC-2544 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu
Catholic University of Daegu
Affinity DataKi: 2.60E+3nMAssay Description:The reaction mixtures contained in various different concentrations of p-NPP as a PTP1B substrate in the presence or absence of the active compound. ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu
Catholic University of Daegu
Affinity DataKi: 2.80E+3nMAssay Description:The reaction mixtures contained in various different concentrations of p-NPP as a PTP1B substrate in the presence or absence of the active compound. ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kyungpook National University
Curated by ChEMBL
Kyungpook National University
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Inhibition of recombinant human Hsp90alpha ATP-binding pocket of N-terminal domain after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Noncompetitive inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu
Catholic University of Daegu
Affinity DataKi: 3.00E+3nM ΔG°: -32.8kJ/mole IC50: 4.80E+3nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Noncompetitive inhibition of human neutrophil elastase using varying levels of MeOSuc-AAPV-pNA as substrate measured after 30 mins by double-reciproc...More data for this Ligand-Target Pair