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Found 12 with Last Name = 'shea' and Initial = 'c'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50401014(CHEMBL2206307)
Affinity DataKi:  8nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  100nMAssay Description:Tested for binding affinity of the compound against kynureninase enzyme from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  130nMAssay Description:Tested for binding affinity of the compound against kynureninase enzyme from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  1.00E+4nMAssay Description:Tested for binding affinity of the compound against kynureninase enzyme from bacterial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50:  1.93nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50:  3.26nMAssay Description:Displacement of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50:  22.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50:  31.0nMAssay Description:Displacement of [3H]NE from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50:  108nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50:  240nMAssay Description:Displacement of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296782((1R,2S,3S,5S)-methyl 8-((E)-3-iodoallyl)-3-p-tolyl...)
Affinity DataKd:  4nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50401015(CHEMBL1947086)
Affinity DataKd:  9nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed