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Found 100 with Last Name = 'shoman' and Initial = 'me'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  0.170nMAssay Description:Relative binding affinity for human estrogen receptor alpha by displacement of [3H]-estradiolMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50410843(CHEMBL5281221)
Affinity DataIC50:  0.510nMAssay Description:Affinity against melatonin receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50410803(CHEMBL5280359)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at rat GnRH receptor assessed as luteinizing hormone release in rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50410844(CHEMBL5289028)
Affinity DataIC50:  1.10nMAssay Description:Concentration required to inhibit the HIV-1 recombinant Reverse Transcriptase (rRT) activity by 50%. Activated calf thymus DNA was used as template p...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50410844(CHEMBL5289028)
Affinity DataIC50:  1.10nMAssay Description:Concentration required to inhibit the HIV-1 recombinant Reverse Transcriptase (rRT) activity by 50%. Activated calf thymus DNA was used as template p...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50573217(CHEMBL4876307)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50410843(CHEMBL5281221)
Affinity DataIC50:  1.5nMAssay Description:Concentration required to inhibit the HIV-1 recombinant Reverse Transcriptase (rRT) activity by 50%. Activated calf thymus DNA was used as template p...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50512074(CHEMBL4575813)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50410836(CHEMBL5274303)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50594749(CHEMBL5170300)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50512074(CHEMBL4575813)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50410803(CHEMBL5280359)
Affinity DataIC50:  4.30nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50594749(CHEMBL5170300)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50410838(CHEMBL5272716)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410804(CHEMBL5287477)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410803(CHEMBL5280359)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50594749(CHEMBL5170300)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50410836(CHEMBL5274303)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50410840(CHEMBL5284623)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50410828(CHEMBL5266387)
Affinity DataIC50:  26nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50573217(CHEMBL4876307)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50292317(CHEMBL4172557)
Affinity DataIC50:  27nMAssay Description:Inhibition of HDAC1 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410800(CHEMBL5206193)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC1 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC6 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50410844(CHEMBL5289028)
Affinity DataIC50:  34nMAssay Description:Affinity against melatonin receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50410845(CHEMBL5273021)
Affinity DataIC50:  38nMAssay Description:Relative binding affinity for sheep uterine estrogen receptor by displacement of [3H]estradiolMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50292331(CHEMBL4168150)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC1 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410828(CHEMBL5266387)
Affinity DataIC50:  39nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410802(CHEMBL5272853)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50410838(CHEMBL5272716)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50410845(CHEMBL5273021)
Affinity DataIC50:  48nMAssay Description:Relative binding affinity for human estrogen receptor beta by displacement of [3H]estradiolMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50594749(CHEMBL5170300)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50292318(CHEMBL4174925)
Affinity DataIC50:  58nMAssay Description:Inhibition of HDAC1 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50594749(CHEMBL5170300)
Affinity DataIC50:  62nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50:  66nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50:  70nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410798(CHEMBL5283543)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  81nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
LigandPNGBDBM50594716(CHEMBL5191956)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))TBA
LigandPNGBDBM50410841(CHEMBL5266767)
Affinity DataIC50:  86nMAssay Description:Binding affinity to DC-SIGN extracellular domain (unknown origin) expressed in Escherichia coli after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50410801(CHEMBL5276251)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  91nMAssay Description:Inhibition of HDAC4 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50594719(CHEMBL5186583)
Affinity DataIC50:  93nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50292317(CHEMBL4172557)
Affinity DataIC50:  99nMAssay Description:Inhibition of HDAC4 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-4B chain(Homo sapiens)TBA
LigandPNGBDBM50410800(CHEMBL5206193)
Affinity DataIC50:  108nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50292317(CHEMBL4172557)
Affinity DataIC50:  114nMAssay Description:Inhibition of HDAC2 in human HeLa cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50410828(CHEMBL5266387)
Affinity DataIC50:  126nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50410843(CHEMBL5281221)
Affinity DataIC50:  130nMAssay Description:Inhibition of AChE in human erythrocytes using acetylthiocholine as substrate measured for 1 minMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50410840(CHEMBL5284623)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
In DepthDetails PubMed
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