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Found 36 with Last Name = 'sivasothy' and Initial = 'y'
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataKi:  560nMAssay Description:Mixed inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataKi:  4.33E+3nMAssay Description:Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataKi:  5.86E+3nMAssay Description:Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataKi:  1.15E+4nMAssay Description:Mixed inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  80nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  220nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  1.00E+3nMAssay Description:Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  1.00E+3nMAssay Description:Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.00E+3nMAssay Description:Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SMS1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SMS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182488(CHEMBL3819036)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182488(CHEMBL3819036)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182488(CHEMBL3819036)
Affinity DataIC50:  6.44E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182488(CHEMBL3819036)
Affinity DataIC50:  6.65E+3nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182489(CHEMBL3818374)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Mus musculus)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of SMS2 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182490(CHEMBL3819024)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182489(CHEMBL3818374)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Mus musculus)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of SMS1 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182490(CHEMBL3819024)
Affinity DataIC50:  3.07E+4nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed