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Found 25 with Last Name = 'stevens' and Initial = 'cv'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human KDR using and Ulight-CAGAGAIETDKEYYTVKD as substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
TargetMyosin-4(Oryctolagus cuniculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  220nMAssay Description:Inhibition of rabbit skeletal muscle myosin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-4(Oryctolagus cuniculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449475(CHEMBL4162111)
Affinity DataIC50:  400nMAssay Description:Inhibition of rabbit skeletal muscle myosin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50012278((2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLAS...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as microtubule assembly after 15 mins by DAPI stainingMore data for this Ligand-Target Pair
TargetMyosin-7(Sus scrofa)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of pig beta cardiac myosin 2 by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonmuscle myosin heavy chain(Gallus gallus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of chicken non-muscle myosin 2b by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-2 heavy chain(Dictyostelium discoideum)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449473(CHEMBL4165503)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Dictyostelium discoideum myosin 2 ATPase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyosin-2 heavy chain(Dictyostelium discoideum)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449475(CHEMBL4162111)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Dictyostelium discoideum myosin 2 ATPase activity by NADH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-14(Mus musculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of mouse non-muscle myosin 2cMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-9(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human non-muscle myosin 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-10(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human non-muscle myosin 2bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-2 heavy chain(Dictyostelium discoideum)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of RLC-phosphorylated Dictyostelium discoideum myosin 2 ATPase activity by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMyosin-2 heavy chain(Dictyostelium discoideum)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449474(CHEMBL4166562)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of Dictyostelium discoideum myosin 2 ATPase activity by NADH-coupled assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyosin-2(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449476(CHEMBL4168922)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human myosin 2a ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-2 heavy chain, non muscle(Acanthamoeba castellanii)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of dephosphorylated Acanthamoeba non muscle myosin 2 by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-XV(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human myosin 15 by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-X(Bos taurus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of bovine myosin x by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-Va(Mus musculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of mouse myosin 5a by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-Ib(Rattus norvegicus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of rat myosin 1b by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin IC heavy chain(Acanthamoeba castellanii)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of dephosphorylated Acanthamoeba muscle myosin 1c by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin heavy chain, non-muscle(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of fruit fly non-muscle myosin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataEC50:  25nMAssay Description:Inhibition of human ERG assessed as reduction of tail currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed