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Found 34 with Last Name = 'stiebing' and Initial = 's'
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91581(Thiaindanone, 3)
Affinity DataIC50:  60nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91580(Thiaindanone, 2)
Affinity DataIC50:  400nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91582(Thiaindanone, 11)
Affinity DataIC50:  400nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91587(Thiaindanone, 1)
Affinity DataIC50:  560nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91584(Thiaindanone, 13)
Affinity DataIC50:  630nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91585(Thiaindanone, 14)
Affinity DataIC50:  1.50E+3nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91583(Thiaindanone, 12)
Affinity DataIC50:  2.30E+3nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209241(4-bromo-1H-indazole | CHEMBL246393)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209244(7-chloro-1H-indazole | CHEMBL247367)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209237(6-bromo-1H-indazole | CHEMBL247365)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91590(Thiaindanone, 19)
Affinity DataIC50: >5.00E+3nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91588(Thiaindanone, 16)
Affinity DataIC50: >5.00E+3nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91586(Thiaindanone, 15)
Affinity DataIC50: >5.00E+3nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie

LigandPNGBDBM91589(Thiaindanone, 17)
Affinity DataIC50: >5.00E+3nMpH: 7.4Assay Description:Inhibitory ability of compounds on AChE activity was evaluated through the use of the spectrometic method of Ellman. Lyophilized electric eel AChE (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390019(CHEMBL2071543)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209239(7-bromo-1H-indazole | CHEMBL439566)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209235(4-iodo-1H-indazole | CHEMBL246534)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209236(6-Chloro-1H-indazole | CHEMBL392184)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390023(CHEMBL2071547)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209243(5-iodo-1H-indazole | CHEMBL391348)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390027(CHEMBL2071551)
Affinity DataIC50:  4.25E+4nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209234(4-chloro-1H-indazole | CHEMBL246533)
Affinity DataIC50:  4.43E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390021(CHEMBL2071545)
Affinity DataIC50:  5.17E+4nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209242(5-chloro-1H-indazole | CHEMBL246746)
Affinity DataIC50:  5.93E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50099398(5-Bromo-1H-indazole | CHEMBL16425 | cid_761929)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390025(CHEMBL2071549)
Affinity DataIC50:  7.25E+4nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390026(CHEMBL2071550)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390024(CHEMBL2071548)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390022(CHEMBL2071546)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50390020(CHEMBL2071544)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nNOS in rat cerebellum homogenates assessed as reduction in conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209238(6-fluoro-1H-indazole | CHEMBL247366)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50099405(5-Fluoro-1H-indazole | CHEMBL16076)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209240(4-fluoro-1H-indazole | CHEMBL392263)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed