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Found 371 with Last Name = 'stowe' and Initial = 'rl'
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  6nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  9nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  45nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  45nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  45nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  45nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50:  60nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  60nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  60nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  60nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50:  60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50:  60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  70nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  70nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  70nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50:  90nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50:  90nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50:  90nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  100nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  100nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  120nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  120nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  120nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163627(SR-3459)
Affinity DataIC50:  150nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  150nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  190nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  190nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  190nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
Affinity DataIC50:  190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50:  190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)
Affinity DataIC50:  220nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)
Affinity DataIC50:  220nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)
Affinity DataIC50:  220nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  230nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  230nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50:  230nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  320nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine

LigandPNGBDBM163627(SR-3459)
Affinity DataIC50:  320nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  320nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50:  380nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468612(US10807944, Compound SR-4372 | US11731934, Compoun...)
Affinity DataIC50:  380nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468613(US10807944, Compound SR-4373 | US11731934, Compoun...)
Affinity DataIC50:  420nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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