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Found 370 with Last Name = 'ward' and Initial = 'am'
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247048(CHEMBL462609 | methyl icosylphosphonofluoridate)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247049(CHEMBL462610 | ethyl 3,5,6-trichloropyridin-2-yl d...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247051(CHEMBL512224 | isopropyl 4-nitrophenyl dodecylphos...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50324698(CHEMBL1222256 | Ethyl octylfluorophosphonate)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247008(CHEMBL499569 | octane-1-sulfonyl fluoride)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132715(CHEMBL97038 | Dodecanesulfonyl fluoride | dodecane...)
Affinity DataIC50:  2nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528203(CHEMBL4434694)
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  2nMAssay Description:Displacement of radioligand from CB1 receptor in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247048(CHEMBL462609 | methyl icosylphosphonofluoridate)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544399(CHEMBL4638273)
Affinity DataIC50:  3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)
Affinity DataIC50: <3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)
Affinity DataIC50:  3nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528209(CHEMBL4526828)
Affinity DataIC50:  3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528196(CHEMBL4575655)
Affinity DataIC50:  3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247051(CHEMBL512224 | isopropyl 4-nitrophenyl dodecylphos...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528203(CHEMBL4434694)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528208(CHEMBL4440168)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528195(CHEMBL4435320)
Affinity DataIC50:  4nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544408(CHEMBL4641207)
Affinity DataIC50:  4nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528203(CHEMBL4434694)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544414(CHEMBL4641530)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528204(CHEMBL4565968)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50324698(CHEMBL1222256 | Ethyl octylfluorophosphonate)
Affinity DataIC50:  5nMAssay Description:Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528205(CHEMBL4468389)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528188(CHEMBL4553210)
Affinity DataIC50:  5nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)
Affinity DataIC50:  6nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544418(CHEMBL4648102)
Affinity DataIC50:  6nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544419(CHEMBL4647724)
Affinity DataIC50:  6nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)
Affinity DataIC50:  6nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 G328V mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528190(CHEMBL4548795)
Affinity DataIC50:  6nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544404(CHEMBL4644571)
Affinity DataIC50:  7nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528208(CHEMBL4440168)
Affinity DataIC50:  7nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)
Affinity DataIC50:  7nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132715(CHEMBL97038 | Dodecanesulfonyl fluoride | dodecane...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)
Affinity DataIC50:  7nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 Q207D mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50528208(CHEMBL4440168)
Affinity DataIC50:  8nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50544405(CHEMBL4634857)
Affinity DataIC50:  8nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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