Affinity DataIC50: 7nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 using [14C]palmitic acid by TLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected Sf9 cells using [14C]oleoyl-CoA after 15 mins by TLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Rattus norvegicus (rat))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of rat DGAT1More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate. More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 165nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
Affinity DataIC50: 237nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
Affinity DataIC50: 253nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center
Curated by ChEMBL
Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair