BindingDB PrimarySearch_ki

Found 112 with Last Name = 'wincza' and Initial = 'e'

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562615(CHEMBL4764756)

Ki: 5.5nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

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3D Structure (crystal)

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562617(CHEMBL4752141)

Ki: 11nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562615(CHEMBL4764756)

Ki: 14nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562617(CHEMBL4752141)

Ki: 14nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562617(CHEMBL4752141)

IC50: 4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562616(CHEMBL4787269)

IC50: 5nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562615(CHEMBL4764756)

IC50: 6nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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3D Structure (crystal)

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562613(CHEMBL4785028)

IC50: 8nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562615(CHEMBL4764756)

IC50: 11nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562640(CHEMBL4743561)

IC50: 12nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562617(CHEMBL4752141)

IC50: 12nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562616(CHEMBL4787269)

IC50: 19nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562614(CHEMBL4757431)

IC50: 21nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562625(CHEMBL4746396)

IC50: 32nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562618(CHEMBL4755524)

IC50: 32nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562628(CHEMBL4749973)

IC50: 37nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562631(CHEMBL4795993)

IC50: 37nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562630(CHEMBL4791136)

IC50: 38nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562628(CHEMBL4749973)

IC50: 40nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562625(CHEMBL4746396)

IC50: 40nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562619(CHEMBL4750622)

IC50: 43nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562631(CHEMBL4795993)

IC50: 47nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562613(CHEMBL4785028)

IC50: 55nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562614(CHEMBL4757431)

IC50: 56nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562640(CHEMBL4743561)

IC50: 56nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562627(CHEMBL4762761)

IC50: 62nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562630(CHEMBL4791136)

IC50: 74nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562639(CHEMBL4789590)

IC50: 75nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562629(CHEMBL4752921)

IC50: 78nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562618(CHEMBL4755524)

IC50: 79nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562629(CHEMBL4752921)

IC50: 80nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562620(CHEMBL4759018)

IC50: 84nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562627(CHEMBL4762761)

IC50: 97nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562626(CHEMBL4752471)

IC50: 100nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562622(CHEMBL4790632)

IC50: 106nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562626(CHEMBL4752471)

IC50: 133nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562619(CHEMBL4750622)

IC50: 163nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562620(CHEMBL4759018)

IC50: 287nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562639(CHEMBL4789590)

IC50: 315nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562623(CHEMBL4763087)

IC50: 340nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562622(CHEMBL4790632)

IC50: 388nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent

PNG

BDBM319770(US10174013, Example 1AE)

IC50: 400nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair

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Details US Patent

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent

PNG

BDBM319772(US10174013, Example 1AI)

IC50: 440nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair

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Details US Patent

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent

PNG

BDBM319757(US10174013, Example 1M)

IC50: 520nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair

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Details US Patent

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent

PNG

BDBM319786(US10174013, Example 1BM)

IC50: 740nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair

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Details US Patent

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent

PNG

BDBM319753(US10174013, Example 8A)

IC50: 770nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Details US Patent

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent

PNG

BDBM319755(US10174013, Example 22A | US10174013, Example 22AB...)

IC50: 850nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Details US Patent

MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562623(CHEMBL4763087)

IC50: 878nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK1 (1 to 424 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562634(CHEMBL4793486)

IC50: 1.07E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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Details Article PubMed

MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ryvu Therapeutics

Curated by ChEMBL

PNG

BDBM50562624(CHEMBL4776712)

IC50: 1.11E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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Details Article PubMed

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