Report error Found 132 Enz. Inhib. hit(s) with Target = 'Neurogenic locus notch homolog protein 1'
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.70nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Notch1 expressed in HEK293 cells coexpressing luciferase reporter measured after 20 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2.10nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2.70nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2.80nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2.90nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2.90nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Notch1 expressed in HEK293 cells coexpressing luciferase reporter measured after 20 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3.20nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3.5nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3.80nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3.90nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3.90nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 4.20nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 4.40nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 4.40nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 4.5nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
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