Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM50230418'
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human ARG1 expressed in Escherichia coli using L-arginine hydrochloride as substrate incubated for 1 hr by colorimetric ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataIC50: 3.60E+3nMAssay Description:Binding affinity to human ARG1 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetArginase-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to human Arg1 at pH 8.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver arginase 1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat ARG1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat Arg1 at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of Sprague-Dawley rat liver arginase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetArginase-1(Mouse)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of mouse arginase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed