Found 4 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50357364' TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human 5-LOX in human peripheral blood mononuclear leukocytes assessed as inhibition of calymycin A23187-stimulated LTB4 production prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Universiti Putra Malaysia
Curated by ChEMBL
Universiti Putra Malaysia
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 5-LOX in calcium ionophore A23187-stimulated NMRI mouse macrophage assessed as inhibition of LTC4 production preincubated for 60 mins b...More data for this Ligand-Target Pair
