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Report error Found 214 of ki for UniProtKB: P09619
TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50237710BDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 13530BDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507078BDBM507078(US11046672, Example 27)
Affinity DataKi:  4.77nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445247BDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  4.79nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445247BDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  4.79nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445240BDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  4.83nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445240BDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  4.83nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507083BDBM507083(US11046672, Example 32)
Affinity DataKi:  4.92nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 531233BDBM531233(US11208381, Example 15 | (Z)-Methyl 3-(((4-(4-(2-(...)
Affinity DataKi:  5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445224BDBM445224(US10669235, Example 15)
Affinity DataKi:  5nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445241BDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  5.02nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445241BDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  5.02nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507090BDBM507090(US11046672, Example 39)
Affinity DataKi:  5.39nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445216BDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  5.76nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445216BDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  5.76nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445230BDBM445230(US10669235, Example 21 | US11208381, Example 21)
Affinity DataKi:  6.11nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445230BDBM445230(US10669235, Example 21 | US11208381, Example 21)
Affinity DataKi:  6.11nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507082BDBM507082(US11046672, Example 31)
Affinity DataKi:  6.58nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507058BDBM507058((Z)-Methyl 3-(((4-((2-(4-(2-hydroxyethyl)piperazin...)
Affinity DataKi:  6.60nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445255BDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  6.65nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445255BDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  6.65nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445242BDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  6.82nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445242BDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  6.82nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445212BDBM445212(US10669235, Example 3 | US11208381, Example 3)
Affinity DataKi:  6.86nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445212BDBM445212(US10669235, Example 3 | US11208381, Example 3)
Affinity DataKi:  6.86nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507089BDBM507089(US11046672, Example 38)
Affinity DataKi:  6.91nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507093BDBM507093(US11046672, Example 42)
Affinity DataKi:  7.06nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507056BDBM507056((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  7.13nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507107BDBM507107(US11046672, Example 56)
Affinity DataKi:  7.19nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507081BDBM507081(US11046672, Example 30)
Affinity DataKi:  7.32nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507080BDBM507080(US11046672, Example 29)
Affinity DataKi:  7.48nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445246BDBM445246(US10669235, Example 37 | US11208381, Example 37)
Affinity DataKi:  7.54nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445246BDBM445246(US10669235, Example 37 | US11208381, Example 37)
Affinity DataKi:  7.54nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507091BDBM507091(US11046672, Example 40)
Affinity DataKi:  7.66nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507079BDBM507079(US11046672, Example 28)
Affinity DataKi:  7.88nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445218BDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  7.89nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445218BDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  7.89nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507122BDBM507122(US11046672, Example 73)
Affinity DataKi:  7.90nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445227BDBM445227(US10669235, Example 18 | US11208381, Example 18)
Affinity DataKi:  7.99nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445227BDBM445227(US10669235, Example 18 | US11208381, Example 18)
Affinity DataKi:  7.99nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445209BDBM445209(US10669235, Nintedanib)
Affinity DataKi:  8nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKi:  8nMAssay Description:Binding affinity to PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50026612BDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKi:  8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50026612BDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKi:  8nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445217BDBM445217(US10669235, Example 8 | US11208381, Example 8)
Affinity DataKi:  8.12nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 445217BDBM445217(US10669235, Example 8 | US11208381, Example 8)
Affinity DataKi:  8.12nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507057BDBM507057((Z)-Methyl 5-methyl-3-(((4-((2-(4-methylpiperazin-...)
Affinity DataKi:  8.31nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507087BDBM507087(US11046672, Example 36)
Affinity DataKi:  8.46nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507084BDBM507084(US11046672, Example 33)
Affinity DataKi:  8.47nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 507077BDBM507077(US11046672, Example 26)
Affinity DataKi:  8.61nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

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