Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 1124
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9063(5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-...)
Affinity DataIC50:  0.600nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9073(2-[9-(Acridin-9-ylamino)-nonyl]-isoindole-1,3-dion...)
Affinity DataIC50:  2.40nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9067(Donepezil-tacrine hybrid 12 | N-[4-({2-[(6-chloro-...)
Affinity DataIC50:  2.80nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9070(2-[6-(Acridin-9-ylamino)-hexyl]-isoindole-1,3-dion...)
Affinity DataIC50:  7.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9068(2-[7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptyl...)
Affinity DataIC50:  10nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9065(Donepezil-tacrine hybrid 10 | N-[6-(6-Chloro-1,2,3...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9066(Donepezil-tacrine hybrid 11 | N-[7-(6-Chloro-1,2,3...)
Affinity DataIC50:  20nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  24nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9063(5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-...)
Affinity DataIC50:  25nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9069(2-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyl]...)
Affinity DataIC50:  29nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9062(5,6-Dimethoxy-2-{[6-(1,2,3,4-tetrahydro-acridin-9-...)
Affinity DataIC50:  50nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9067(Donepezil-tacrine hybrid 12 | N-[4-({2-[(6-chloro-...)
Affinity DataIC50:  75nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9073(2-[9-(Acridin-9-ylamino)-nonyl]-isoindole-1,3-dion...)
Affinity DataIC50:  90nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9069(2-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyl]...)
Affinity DataIC50:  93nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9064(2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]...)
Affinity DataIC50:  98nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9062(5,6-Dimethoxy-2-{[6-(1,2,3,4-tetrahydro-acridin-9-...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  167nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9065(Donepezil-tacrine hybrid 10 | N-[6-(6-Chloro-1,2,3...)
Affinity DataIC50:  220nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9064(2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]...)
Affinity DataIC50:  504nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9066(Donepezil-tacrine hybrid 11 | N-[7-(6-Chloro-1,2,3...)
Affinity DataIC50:  660nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9071(2-[7-(Acridin-9-ylamino)-heptyl]-isoindole-1,3-dio...)
Affinity DataIC50:  711nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9070(2-[6-(Acridin-9-ylamino)-hexyl]-isoindole-1,3-dion...)
Affinity DataIC50:  870nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  930nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9072(2-[8-(Acridin-9-ylamino)-octyl]-isoindole-1,3-dion...)
Affinity DataIC50:  1.01E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9072(2-[8-(Acridin-9-ylamino)-octyl]-isoindole-1,3-dion...)
Affinity DataIC50:  1.14E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9071(2-[7-(Acridin-9-ylamino)-heptyl]-isoindole-1,3-dio...)
Affinity DataIC50:  1.55E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9068(2-[7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptyl...)
Affinity DataIC50:  3.01E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed