Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50004178
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005781BDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479788BDBM50479788(CHEMBL486750)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005781BDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataEC50:  7.90nMAssay Description:Inhibition of Hsp90 in human A2058 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479790BDBM50479790(CHEMBL486547)
Affinity DataIC50: 17nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005781BDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataIC50: 18nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479788BDBM50479788(CHEMBL486750)
Affinity DataEC50:  18nMAssay Description:Inhibition of Hsp90 in human A2058 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479788BDBM50479788(CHEMBL486750)
Affinity DataIC50: 19nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479788BDBM50479788(CHEMBL486750)
Affinity DataIC50: 20nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005781BDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataIC50: 24nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479790BDBM50479790(CHEMBL486547)
Affinity DataIC50: 27nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479787BDBM50479787(CHEMBL471818)
Affinity DataIC50: 30nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479788BDBM50479788(CHEMBL486750)
Affinity DataIC50: 34nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479790BDBM50479790(CHEMBL486547)
Affinity DataEC50:  41nMAssay Description:Inhibition of Hsp90 in human A2058 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479790BDBM50479790(CHEMBL486547)
Affinity DataIC50: 42nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479790BDBM50479790(CHEMBL486547)
Affinity DataIC50: 50nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479802BDBM50479802(CHEMBL487771)
Affinity DataIC50: 70nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479797BDBM50479797(CHEMBL471817)
Affinity DataIC50: 73nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479804BDBM50479804(CHEMBL469506)
Affinity DataIC50: 150nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479786BDBM50479786(CHEMBL470174)
Affinity DataIC50: 150nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479783BDBM50479783(CHEMBL512333)
Affinity DataIC50: 300nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479795BDBM50479795(CHEMBL472467)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479801BDBM50479801(CHEMBL450227)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479791BDBM50479791(CHEMBL511160)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479796BDBM50479796(CHEMBL471019)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479785BDBM50479785(CHEMBL470173)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479800BDBM50479800(CHEMBL470365)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479784BDBM50479784(CHEMBL470810)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 227591BDBM227591(PA7)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479780BDBM50479780(CHEMBL445947)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479803BDBM50479803(CHEMBL511998)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479781BDBM50479781(CHEMBL511310)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479789BDBM50479789(CHEMBL520382)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479799BDBM50479799(CHEMBL471409)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479798BDBM50479798(CHEMBL472658)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479793BDBM50479793(CHEMBL471618)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479805BDBM50479805(CHEMBL521041)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479782BDBM50479782(CHEMBL472262)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479792BDBM50479792(CHEMBL513225)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479778BDBM50479778(CHEMBL453447)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479794BDBM50479794(CHEMBL443200)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479779BDBM50479779(CHEMBL472659)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed