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Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 3019
TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26975(2-benzoylquinazoline analogue, (rac)-17 | N-{4-[(2...)
Affinity DataKi:  2.10nM ΔG°:  -49.5kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26973((1R,2S)-2-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-me...)
Affinity DataKi:  43nM ΔG°:  -42.0kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26974(4-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquin...)
Affinity DataKi:  60nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26971(3-[6-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylq...)
Affinity DataKi:  89nM ΔG°:  -40.2kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26960(4-aminoquinazoline derivative, 7c | N-(6-aminohexy...)
Affinity DataKi:  120nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26956(N-(6-aminohexyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]...)
Affinity DataKi:  133nM ΔG°:  -39.2kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26977(2-benzoylquinazoline analogue, (1S, 2R)-17 | N-(4-...)
Affinity DataKi:  140nM ΔG°:  -39.1kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26968((1S,2R)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-m...)
Affinity DataKi:  150nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26974(4-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquin...)
Affinity DataKi:  152nM ΔG°:  -38.9kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26972(3-[4-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylq...)
Affinity DataKi:  160nM ΔG°:  -38.8kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26969(1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylqui...)
Affinity DataKi:  162nM ΔG°:  -38.8kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26959(4-aminoquinazoline derivative, 7b | N-(6-aminohexy...)
Affinity DataKi:  170nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26967((1S,2S)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-m...)
Affinity DataKi:  180nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26958(4-aminoquinazoline derivative, 7a | N-(6-aminohexy...)
Affinity DataKi:  180nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26965(4-aminoquinazoline derivative, 7h | N-(4-aminobuty...)
Affinity DataKi:  194nM ΔG°:  -38.3kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26961(4-aminoquinazoline derivative, 7d | N-(6-aminohexy...)
Affinity DataKi:  200nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26968((1S,2R)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-m...)
Affinity DataKi:  200nM ΔG°:  -38.2kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26973((1R,2S)-2-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-me...)
Affinity DataKi:  220nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26960(4-aminoquinazoline derivative, 7c | N-(6-aminohexy...)
Affinity DataKi:  232nM ΔG°:  -37.9kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26966(4-aminoquinazoline derivative, 7i | N-(2-aminoethy...)
Affinity DataKi:  240nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26965(4-aminoquinazoline derivative, 7h | N-(4-aminobuty...)
Affinity DataKi:  250nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(2-benzoylquinazoline analogue, (1S, 2R)-17 | N-(4-...)
Affinity DataKi:  270nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26963(4-aminoquinazoline derivative, 7f | N-(6-aminohexy...)
Affinity DataKi:  292nM ΔG°:  -37.3kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26964(4-aminoquinazoline derivative, 7g | N-(6-aminohexy...)
Affinity DataKi:  294nM ΔG°:  -37.3kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26971(3-[6-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylq...)
Affinity DataKi:  300nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26970(1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylqui...)
Affinity DataKi:  300nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26975(2-benzoylquinazoline analogue, (rac)-17 | N-{4-[(2...)
Affinity DataKi:  310nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  330nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26963(4-aminoquinazoline derivative, 7f | N-(6-aminohexy...)
Affinity DataKi:  380nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26964(4-aminoquinazoline derivative, 7g | N-(6-aminohexy...)
Affinity DataKi:  380nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26958(4-aminoquinazoline derivative, 7a | N-(6-aminohexy...)
Affinity DataKi:  383nM ΔG°:  -36.6kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26956(N-(6-aminohexyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]...)
Affinity DataKi:  410nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26969(1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylqui...)
Affinity DataKi:  410nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26961(4-aminoquinazoline derivative, 7d | N-(6-aminohexy...)
Affinity DataKi:  420nM ΔG°:  -36.4kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  510nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26967((1S,2S)-1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-m...)
Affinity DataKi:  538nM ΔG°:  -35.8kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26962(4-aminoquinazoline derivative, 7e | N-(6-aminohexy...)
Affinity DataKi:  653nM ΔG°:  -35.3kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26970(1-N-{2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylqui...)
Affinity DataKi:  795nM ΔG°:  -34.8kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26959(4-aminoquinazoline derivative, 7b | N-(6-aminohexy...)
Affinity DataKi:  808nM ΔG°:  -34.8kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26962(4-aminoquinazoline derivative, 7e | N-(6-aminohexy...)
Affinity DataKi:  930nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Nippon Shinyaku

LigandPNGBDBM26966(4-aminoquinazoline derivative, 7i | N-(2-aminoethy...)
Affinity DataKi:  972nM ΔG°:  -34.3kJ/molepH: 7.8 T: 25°CAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(2-benzoylquinazoline analogue, (1S, 2R)-17 | N-(4-...)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26972(3-[4-({2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylq...)
Affinity DataKi:  2.30E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(2-benzoylquinazoline analogue, (1S, 2R)-17 | N-(4-...)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26977(2-benzoylquinazoline analogue, (1S, 2R)-17 | N-(4-...)
Affinity DataKi:  3.60E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26975(2-benzoylquinazoline analogue, (rac)-17 | N-{4-[(2...)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Nippon Shinyaku

LigandPNGBDBM26976(2-benzoylquinazoline analogue, (1R, 2S)-17 | N-(4-...)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed