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Found 21 Enz. Inhib. hit(s) with all data for entry = 50032298
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326835(2-(2-Bromobenzyl)-6-methoxy-tetralone | CHEMBL1253...)
Affinity DataIC50:  59nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  520nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50155480(6-Methoxy-2-(2-methyl-benzyl)-3,4-dihydro-2H-napht...)
Affinity DataIC50:  900nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326834(2-(2-Ethylbenzyl)-6-methoxy-tetralone | CHEMBL1253...)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326833(2-(2-Trifluoromethylbenzyl)-6-methoxy-tetralone | ...)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50155470(2-biphenyl-2-ylmethyl-6-hydroxy-3,4-dihydro-2H-nap...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of CYP24A1 in rat kidney mitochondriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50155468(2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-...)
Affinity DataIC50:  4.33E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326832((E)-2-(2-(E)-Styrylbenzylidene)-6-methoxy-tetralon...)
Affinity DataIC50:  5.08E+3nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326833(2-(2-Trifluoromethylbenzyl)-6-methoxy-tetralone | ...)
Affinity DataIC50:  5.34E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326832((E)-2-(2-(E)-Styrylbenzylidene)-6-methoxy-tetralon...)
Affinity DataIC50:  5.69E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326834(2-(2-Ethylbenzyl)-6-methoxy-tetralone | CHEMBL1253...)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326837((E)-2-(2-Ethylbenzylidene)-6-methoxy-tetralone | C...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326836((E)-2-(2-Trifluoromethylbenzylidene)-6-methoxy-tet...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326835(2-(2-Bromobenzyl)-6-methoxy-tetralone | CHEMBL1253...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of CYP24A1 in rat kidney mitochondriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326841(2-(2-Phenethylbenzyl)-6-methoxy-tetralone | CHEMBL...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326838((E)-2-(biphenyl-2-ylmethylene)-6-methoxy-3,4-dihyd...)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50155468(2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-...)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326839(2-(biphenyl-2-ylmethyl)-6-methoxy-3,4-dihydronapht...)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326840(2-(2-(E)-Styrylbenzyl)-6-methoxy-tetralone | CHEMB...)
Affinity DataIC50:  3.43E+5nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50155472(6-Methoxy-2-[1-o-tolyl-meth-(E)-ylidene]-3,4-dihyd...)
Affinity DataIC50:  4.80E+5nMAssay Description:Inhibition of CYP24A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed