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Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 8410
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246595(Camptothecin (CPT))
Affinity DataIC50:  2.80E+3nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246595(Camptothecin (CPT))
Affinity DataIC50:  4.20E+3nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246594(Bi-lawsone analog, 3d)
Affinity DataIC50:  1.30E+4nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246593(Bi-lawsone analog, 3c)
Affinity DataIC50:  1.40E+4nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246591(Bi-lawsone analog, 3a)
Affinity DataIC50:  1.60E+4nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246592(Bi-lawsone analog, 3b)
Affinity DataIC50:  1.70E+4nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246592(Bi-lawsone analog, 3b)
Affinity DataIC50:  3.75E+4nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246591(Bi-lawsone analog, 3a)
Affinity DataIC50:  5.10E+4nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246594(Bi-lawsone analog, 3d)
Affinity DataIC50:  7.00E+4nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246593(Bi-lawsone analog, 3c)
Affinity DataIC50:  7.40E+4nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed