Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50002762
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462606BDBM50462606(CHEMBL4249022)
Affinity DataIC50: 2nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462612BDBM50462612(CHEMBL4246480)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462622BDBM50462622(CHEMBL4238198)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462613BDBM50462613(CHEMBL4246864)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462611BDBM50462611(CHEMBL4241473)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462620BDBM50462620(CHEMBL4251272)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462605BDBM50462605(CHEMBL4245244)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462619BDBM50462619(CHEMBL4238378)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462603BDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069989BDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398609BDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462604BDBM50462604(CHEMBL4242666)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462625BDBM50462625(CHEMBL4243375 | US11542283, Compound IV-8)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462621BDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462610BDBM50462610(CHEMBL4249503)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462621BDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50: 11nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462603BDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50: 13nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462618BDBM50462618(CHEMBL4249917)
Affinity DataIC50: 13nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462614BDBM50462614(CHEMBL4238931)
Affinity DataIC50: 20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462624BDBM50462624(CHEMBL4248689)
Affinity DataIC50: 21nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462623BDBM50462623(CHEMBL4246922)
Affinity DataIC50: 27nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462615BDBM50462615(CHEMBL4243132)
Affinity DataIC50: 28nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462616BDBM50462616(CHEMBL4249453)
Affinity DataIC50: 31nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462607BDBM50462607(CHEMBL4239365)
Affinity DataIC50: 43nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462609BDBM50462609(CHEMBL4250217)
Affinity DataIC50: 75nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069989BDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 97nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462602BDBM50462602(CHEMBL1813227)
Affinity DataIC50: 304nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462608BDBM50462608(CHEMBL4244424)
Affinity DataIC50: 387nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462617BDBM50462617(CHEMBL4245648)
Affinity DataIC50: 594nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462603BDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069989BDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Nanjing Forestry University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462621BDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed