Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50010629
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540739(CHEMBL4632807 | US11472795, Example 1)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540740(CHEMBL4643920 | US11472795, Example 3)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 10nMAssay Description:Inhibition of human LynB using His-tagged Rb truncated protein as substrate incubated for 30 mins in presence of ATP at Km concentration by HTRF assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 10nMAssay Description:Inhibition of human DYRK1A in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GSK3alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate incubated for 60 mins in presence of ATP at Km concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 11nMAssay Description:Inhibition of human GRK2 in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 13nMAssay Description:Inhibition of human CLK1 in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540729(CHEMBL4641082 | US11472795, Example 7)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540737(CHEMBL4633136 | US11472795, Example 10)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50134187(CHEMBL3735506 | US9611249, Compound 8 | US11472795...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540730(CHEMBL4635680 | US11472795, Example 12)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540733(CHEMBL4633727)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540738(CHEMBL4638321 | US11472795, Example 23)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540731(CHEMBL4634867 | US11472795, Example 15)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 27nMAssay Description:Inhibition of human CDK2/cyclinA using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate incubated for 30 mins in presence of ATP by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540742(CHEMBL4636306 | US11472795, Example 22)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540734(CHEMBL4633607)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50267626(AZ-11548415 | AZD-1080)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant full length human GSK3beta expressed in Sf21 insect cells using biotinylated-AAEELDSRAGS(PO3H2)PQL peptide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540743(CHEMBL4641148 | US11472795, Example 18)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540736(CHEMBL4645145)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50134187(CHEMBL3735506 | US9611249, Compound 8 | US11472795...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540732(CHEMBL4635900 | US11472795, Example 13)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50229962(N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)U...)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant full length human GSK3beta expressed in Sf21 insect cells using biotinylated-AAEELDSRAGS(PO3H2)PQL peptide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540735(CHEMBL4633141 | US11472795, Example 25)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540739(CHEMBL4632807 | US11472795, Example 1)
Affinity DataIC50: 860nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540733(CHEMBL4633727)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540736(CHEMBL4645145)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) transfected in HEK cells co-transfected with tau assessed as reduction in tau phosphorylation incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540729(CHEMBL4641082 | US11472795, Example 7)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540731(CHEMBL4634867 | US11472795, Example 15)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540740(CHEMBL4643920 | US11472795, Example 3)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540734(CHEMBL4633607)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540732(CHEMBL4635900 | US11472795, Example 13)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540735(CHEMBL4633141 | US11472795, Example 25)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540737(CHEMBL4633136 | US11472795, Example 10)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540730(CHEMBL4635680 | US11472795, Example 12)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540743(CHEMBL4641148 | US11472795, Example 18)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540742(CHEMBL4636306 | US11472795, Example 22)
Affinity DataIC50: 4.71E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540738(CHEMBL4638321 | US11472795, Example 23)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50540741(CHEMBL4640019)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current by measuring tail current amplitude measured after deploarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed