Compile Data Set for Download or QSAR
Report error Found 270 Enz. Inhib. hit(s) with all data for entry = 50011064
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]-ketanserin from human HT2A receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  0.525nMAssay Description:Displacement of [3H]-ketanserin from human HT2A receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 0.810nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 0.813nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human HT2A receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human HT2A receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  5.20nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  5.20nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544625(CHEMBL4632373)
Affinity DataEC50:  7.90nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544625(CHEMBL4632373)
Affinity DataEC50:  7.90nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544622(CHEMBL4645305)
Affinity DataEC50:  8.70nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544622(CHEMBL4645305)
Affinity DataEC50:  8.70nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544624(CHEMBL4643961)
Affinity DataEC50:  9nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544624(CHEMBL4643961)
Affinity DataEC50:  9.10nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544626(CHEMBL4646835)
Affinity DataEC50:  9.90nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544626(CHEMBL4646835)
Affinity DataEC50:  10nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544623(CHEMBL4635729)
Affinity DataEC50:  11nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544623(CHEMBL4635729)
Affinity DataEC50:  12nMAssay Description:Positive modulator activity at human mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544621(CHEMBL4646555)
Affinity DataEC50:  19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544621(CHEMBL4646555)
Affinity DataEC50:  19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544627(CHEMBL4636980)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50267632(4-(3-Hydroxy-2-methoxy-benzoyl)-1-(2-p-fluoropheny...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544625(CHEMBL4632373)
Affinity DataEC50:  24nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
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