Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50018544
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ADAMTS-5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 30nMAssay Description:Inhibition of ADAMTS-4 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 40nMAssay Description:Inhibition of ADAMTS-5 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human ADAMTS-5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50341825(2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydr...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  321nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50341825(2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydr...)
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant human ADAMTS-5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of MMP12 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126057((2R,3S)-N*4*-Hydroxy-2-(3-hydroxy-benzyl)-N*1*-((1...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  2.68E+3nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609412(CHEMBL5266587)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  3.63E+3nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609424(CHEMBL5290512)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi:  4.14E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  4.43E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  4.77E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  5.57E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  6.34E+3nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi: >8.00E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi: >8.00E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609418(CHEMBL5269839)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi: >8.10E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  8.71E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609410(CHEMBL5280915)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human ADAMTS-5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 9.58E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609417(CHEMBL5286469)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  1.04E+4nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of recombinant human ADAMTS-5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609411(CHEMBL5273632)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609422(CHEMBL5267646)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609420(CHEMBL5290839)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609423(CHEMBL5288351)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609415(CHEMBL5268743)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50609416(CHEMBL5282276)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of full length recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
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