Compile Data Set for Download or QSAR
Report error Found 226 Enz. Inhib. hit(s) with all data for entry = 9552
TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473831BDBM473831(2-Chloro-4-(5,5-dimethyl-7- oxo-4,5,6,7-tetrahydro...)
Affinity DataIC50: 1.30nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473948BDBM473948(3-(1,2,3,4-Tetrahydro- naphthalen-2-yl)-3,5,6,7- t...)
Affinity DataIC50: 2.80nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473830BDBM473830(3-(3,4-Dichloro-phenyl)-6,6,- dimethyl-3,5,6,7-tet...)
Affinity DataIC50: 3.10nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473832BDBM473832(3-(2,3-Dichloro-phenyl)-6,6- dimethyl-3,5,6,7-tetr...)
Affinity DataIC50: 3.80nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473817BDBM473817(4-(7-Oxospiro[4,6- dihydrobenzimidazole-5,1'- cycl...)
Affinity DataIC50: 3.80nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473833BDBM473833(3-(2,4-Dichloro-phenyl)-6,6- dimethyl-3,5,6,7-tetr...)
Affinity DataIC50: 4.20nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473900BDBM473900(3-(4-Chloro-3-fluoro- phenyl)-6,6-dimethyl- 3,5,6,...)
Affinity DataIC50: 4.70nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473839BDBM473839(3-(3-Chloro-4-fluoro- phenyl)-6,6-dimethyl- 3,5,6,...)
Affinity DataIC50: 4.80nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473820BDBM473820(3-(3-Chloro-4-cyano)-6,6- spirocyclopropyl-3,5,6,7...)
Affinity DataIC50: 5nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473916BDBM473916(3-(3,4-Dichloro-phenyl)- 3,5,6,7-tetrahydro- benzo...)
Affinity DataIC50: 5.5nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473909BDBM473909(4-(5,5-Dimethyl-7-oxo- 4,5,6,7-tetrahydro- benzoim...)
Affinity DataIC50: 6.60nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473822BDBM473822(1-(3-Chloro-4-cyano- phenyl)-7-oxo-4,5,6,7- tetrah...)
Affinity DataIC50: 7.30nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473821BDBM473821(3-(4-Cyanophenyl)-6,6- spirocyclpropyl-3,5,6,7- te...)
Affinity DataIC50: 8.5nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473965BDBM473965(2-Chloro-4-(7-oxo-4,5,6,7- tetrahydro-benzoimidazo...)
Affinity DataIC50: 8.70nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473828BDBM473828(3-(3,4-Difluoro-phenyl)-6,6- dimethyl-3,5,6,7-tetr...)
Affinity DataIC50: 10nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473946BDBM473946(6,6-Dimethyl-3-(1,2,3,4- tetrahydro-naphthalen-2-y...)
Affinity DataIC50: 10nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473818BDBM473818(2-Methyl-4-(7-oxospiro[4,6- dihydrobenzimidazole-5...)
Affinity DataIC50: 10nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473919BDBM473919(3-(4-Chloroophenyl)-6,6- spirocyclopropyl-3,5,6,7-...)
Affinity DataIC50: 10nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473802BDBM473802(3-(2,3-Dihydro-benzofuran- 5-yl)-3,5,6,7-tetrahydr...)
Affinity DataIC50: 11nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473920BDBM473920(3-(4-Cyano, 3- chlorophenyl)-6,6- spirocyclobutyl-...)
Affinity DataIC50: 12nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473962BDBM473962(4-(6,6-Dimethyl-7-oxo- 4,5,6,7-tetrahydro- benzoim...)
Affinity DataIC50: 14nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473901BDBM473901(3-(4-Chloro-phenyl)-6,6- dimethyl-3,5,6,7-tetrahyd...)
Affinity DataIC50: 15nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473921BDBM473921(3-(1-Methyl-2-oxo-3,4- dihydroquinolin-6- yl)spiro...)
Affinity DataIC50: 16nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473826BDBM473826(3-(4-Cyanophenyl)-6,6-(3- tetrahydrofuran)-3,5,6,7...)
Affinity DataIC50: 16nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473825BDBM473825(3-(4-Cyanophenyl)-6,6-(3- tetrahydrofuran)-3,5,6,7...)
Affinity DataIC50: 16nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473911BDBM473911(4-(5,5-Dimethyl-7-oxo- 4,5,6,7-tetrahydro- benzoim...)
Affinity DataIC50: 17nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473968BDBM473968(2-Chloro-4-(5- hydroxymethyl-7-oxo- 4,5,6,7-tetrah...)
Affinity DataIC50: 18nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473898BDBM473898(3-(3-Chloro-phenyl)-6,6- dimethyl-3,5,6,7-tetrahyd...)
Affinity DataIC50: 19nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473809BDBM473809(4-(7-Oxo-4,5,6,7-tetrahydro- benzoimidazol-1-yl)- ...)
Affinity DataIC50: 19nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473918BDBM473918(3-(3,4-Difluoro-phenyl)-6,6- spirocyclopropyl-3,5,...)
Affinity DataIC50: 20nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473949BDBM473949(3-Indan-2-yl-3,5,6,7- tetrahydro-benzoimidazol-4- ...)
Affinity DataIC50: 21nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473903BDBM473903(3-(4-Fluoro-phenyl)-6,6- dimethyl-3,5,6,7-tetrahyd...)
Affinity DataIC50: 21nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473950BDBM473950(4-(5,5-Dimethyl-7-oxo- 4,5,6,7-tetrahydro- benzoim...)
Affinity DataIC50: 22nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473915BDBM473915(6,6-Dimethyl-3-p-tolyl- 3,5,6,7-tetrahydro- benzoi...)
Affinity DataIC50: 22nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473834BDBM473834(3-(3,5-Dichloro-phenyl)-6,6- dimethyl-3,5,6,7-tetr...)
Affinity DataIC50: 22nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473963BDBM473963(4-(6-Methyl-7-oxo-4,5,6,7- tetrahydro-benzoimidazo...)
Affinity DataIC50: 24nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473929BDBM473929(3-Cyclohexylmethyl-6,6- dimethyl-3,5,6,7-tetrahydr...)
Affinity DataIC50: 24nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473936BDBM473936(6,6-Dimethyl-3-(6,7,8,9- tetrahydro-5H- benzocyclo...)
Affinity DataIC50: 24nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473927BDBM473927(3-(6-Methoxy-1,2,3,4- tetrahydro-naphthalen-2-yl)-...)
Affinity DataIC50: 24nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473960BDBM473960(3-[4-(1-Hydroxy-1-methyl- ethyl)-benzyl]-6,6-dimet...)
Affinity DataIC50: 25nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473923BDBM473923(trans-4-(7-Oxo-5,6-dihydro- 4H-benzimidazol-1- yl)...)
Affinity DataIC50: 30nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473967BDBM473967((R)-1-(3-Chloro-4-cyano- phenyl)-7-oxo-4,5,6,7- te...)
Affinity DataIC50: 32nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473808BDBM473808(3-Cyclopropyl-4-(7-oxo- 4,5,6,7-tetrahydro- benzoi...)
Affinity DataIC50: 34nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473908BDBM473908(3-Benzo[1,3]dioxol-5-yl-6,6- dimethyl-3,5,6,7-tetr...)
Affinity DataIC50: 34nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473939BDBM473939(4-(5,5-Dimethyl-7-oxo- 4,5,6,7-tetrahydro- benzoim...)
Affinity DataIC50: 34nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473803BDBM473803(3-(1-Acetyl-1,2,3,4- tetrahydro-quinolin-6-yl)- 3,...)
Affinity DataIC50: 37nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473814BDBM473814(3-(3-Chloro-4-cyano- phenyl)-6,6-3-o- tetrahydropy...)
Affinity DataIC50: 44nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473819BDBM473819(3-(1-Methyl-2-oxo-3,4- dihydroquinolin-6- yl)spiro...)
Affinity DataIC50: 47nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473945BDBM473945(3-Indan-4-yl-6,6-dimethyl- 3,5,6,7-tetrahydro- ben...)
Affinity DataIC50: 47nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 473805BDBM473805(3-(1-Methyl-1H-indazol-6- yl)-3,5,67,-tetrahydro- ...)
Affinity DataIC50: 48nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent

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