Compile Data Set for Download or QSAR
Report error Found 923 Enz. Inhib. hit(s) with all data for entry = 9891
TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418177BDBM418177(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50: 1.10nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418281BDBM418281(US10457669, Example 1072 | (2R)-2-[6-(5-chloro-2-{...)
Affinity DataIC50: 1.20nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417953BDBM417953(US10457669, Example 614 | US11001575, Example 616)
Affinity DataIC50: 1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417999BDBM417999(US10457669, Example 675 | US11001575, Example 675)
Affinity DataIC50: 1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418188BDBM418188(2-[(1R)-5-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50: 1.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418223BDBM418223((2R)-2-(3-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50: 1.40nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418230BDBM418230((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50: 1.40nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418266BDBM418266(US10457669, Example 1048 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418229BDBM418229((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin...)
Affinity DataIC50: 1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418305BDBM418305(US10457669, Example 1112 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418192BDBM418192(US10457669, Example 952 | US10457669, Example 953 ...)
Affinity DataIC50: 1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418307BDBM418307(US10457669, Example 1114 | (2R)-2-(6-}5-chloro-2-[...)
Affinity DataIC50: 1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418133BDBM418133(US10457669, Example 872 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418200BDBM418200(US10457669, Example 962 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418300BDBM418300(US10457669, Example 1105 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418276BDBM418276(US10457669, Example 1063 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418298BDBM418298(US10457669, Example 1095 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 497509BDBM497509(2-(6-{5-chloro-2-[(oxan- 4-yl)amino]pyrimidin-4- y...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418308BDBM418308(US10457669, Example 1115 | (2R)-2-[6-(5-chloro-2-{...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417753BDBM417753(US10457669, Example 383 | 2-[6-(5-chloro-2-{[3- (h...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417813BDBM417813(US10457669, Example 451 | US11001575, Example 451)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417960BDBM417960(US10457669, Example 621 | US11001575, Example 621)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418105BDBM418105(US10457669, Example 828 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417895BDBM417895(US10457669, Example 545 | US11001575, Example 545)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418178BDBM418178(2-[(1R)-5-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418089BDBM418089(US10457669, Example 803 | (2R)-2-{6-[5-chloro-2- (...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 498075BDBM498075((2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimid i...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417975BDBM417975(US10457669, Example 642 | US11001575, Example 642)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418273BDBM418273(US10457669, Example 1058 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418192BDBM418192(US10457669, Example 952 | US10457669, Example 953 ...)
Affinity DataIC50: 1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418147BDBM418147(US10457669, Example 891 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418091BDBM418091(US10457669, Example 805 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417615BDBM417615(2-(6-{5-chloro-2-[(oxan- 4-yl)amino]pyrimidin-4- y...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418270BDBM418270(US10457669, Example 1054 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418173BDBM418173((2R)-2-(6-{5-chloro-2-[(2- methylpyrimidin-4-yl)am...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418144BDBM418144(US10457669, Example 887 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418160BDBM418160((2R)-2-(6-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50: 1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 497778BDBM497778(US11001575, Example 596)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417807BDBM417807(US10457669, Example 443 | 2-(6-{5-chloro-2- [(oxan...)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418097BDBM418097(US10457669, Example 819 | (2R)-2-[6-(5-chloro-2-{[...)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417704BDBM417704(2-[6-(5-chloro-2- {[trans-4- methoxycyclohexyl] am...)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418237BDBM418237(US10457669, Example 1005 | (2R)-2-(6-{5-chloro-2-[...)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417399BDBM417399(2-(6-{5-chloro-2- [(oxan-4-yl)amino] pyrimidin-4-y...)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418101BDBM418101(US10457669, Example 823 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417675BDBM417675(2-(6-{5-chloro-2-[(oxan- 4-yl)amino]pyrimidin-4- y...)
Affinity DataIC50: 2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 417819BDBM417819(US10457669, Example 463 | US11001575, Example 463)
Affinity DataIC50: 2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418090BDBM418090(US10457669, Example 804 | (2R)-2-(6-{5-chloro-2-[(...)
Affinity DataIC50: 2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 497758BDBM497758(2-(6-{5-chloro-2- [(oxan-4- yl)amino]pyrimidin-4-...)
Affinity DataIC50: 2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418018BDBM418018(US10457669, Example 697 | US11001575, Example 697)
Affinity DataIC50: 2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 418075BDBM418075(US10457669, Example 784 | 2-(6-{5-chloro-2-[(oxan-...)
Affinity DataIC50: 2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

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