Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 10334
TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528557BDBM528557(US11192859, Compound 247)
Affinity DataKd:  2nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528548BDBM528548(US11192859, Compound 229)
Affinity DataKd:  3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528555BDBM528555(US11192859, Compound 242)
Affinity DataKd:  8nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528546BDBM528546(US11192859, Compound 227)
Affinity DataKd:  10nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528554BDBM528554(US11192859, Compound 241)
Affinity DataKd:  11nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528553BDBM528553(US11192859, Compound 239)
Affinity DataKd:  13nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528552BDBM528552(US11192859, Compound 238)
Affinity DataKd:  16nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528539BDBM528539(US11192859, Compound 220)
Affinity DataKd:  22nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528545BDBM528545(US11192859, Compound 226)
Affinity DataKd:  25nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528536BDBM528536(US11192859, Compound 215)
Affinity DataKd:  27nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528560BDBM528560(US11192859, Compound 252)
Affinity DataKd:  29nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528541BDBM528541(US11192859, Compound 222)
Affinity DataKd:  32nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528543BDBM528543(US11192859, Compound 224)
Affinity DataKd:  32nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528540BDBM528540(US11192859, Compound 221)
Affinity DataKd:  34nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528535BDBM528535(US11192859, Compound 214)
Affinity DataKd:  34nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528549BDBM528549(US11192859, Compound 231)
Affinity DataKd:  47nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528556BDBM528556(US11192859, Compound 244)
Affinity DataKd:  54nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528551BDBM528551(US11192859, Compound 236)
Affinity DataKd:  56nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528542BDBM528542(US11192859, Compound 223)
Affinity DataKd:  72nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528550BDBM528550(US11192859, Compound 235)
Affinity DataKd:  76nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528537BDBM528537(US11192859, Compound 218)
Affinity DataKd:  80nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528558BDBM528558(US11192859, Compound 250)
Affinity DataKd:  81nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528538BDBM528538(US11192859, Compound 219)
Affinity DataKd:  89nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528544BDBM528544(US11192859, Compound 225)
Affinity DataKd:  122nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528547BDBM528547(US11192859, Compound 228)
Affinity DataKd:  122nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528563BDBM528563(US11192859, Compound 255)
Affinity DataKd:  137nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528559BDBM528559(US11192859, Compound 251)
Affinity DataKd:  168nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528561BDBM528561(US11192859, Compound 253)
Affinity DataKd:  1.30E+3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528562BDBM528562(US11192859, Compound 254)
Affinity DataKd:  1.34E+3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528534BDBM528534(US11192859, Compound 109)
Affinity DataKd:  1.90E+3nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528564BDBM528564(US11192859, Compound 256)
Affinity DataKd:  5.80E+3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528533BDBM528533(US11192859, Compound 108)
Affinity DataKd:  1.10E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528526BDBM528526(US11192859, Compound 103)
Affinity DataKd:  1.80E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528525BDBM528525(US11192859, Compound 102)
Affinity DataKd:  2.90E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528530BDBM528530(US11192859, Compound 106)
Affinity DataKd:  3.40E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528521BDBM528521(US11192859, Compound 5)
Affinity DataKd:  4.10E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528524BDBM528524(US11192859, Compound 101)
Affinity DataKd:  4.30E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528532BDBM528532(US11192859, Compound 107)
Affinity DataKd:  4.40E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528528BDBM528528(US11192859, Compound 105)
Affinity DataKd:  4.50E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528520BDBM528520(US11192859, Compound 4)
Affinity DataKd:  5.60E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528527BDBM528527(US11192859, Compound 104)
Affinity DataKd:  6.00E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528523BDBM528523(US11192859, Compound 7)
Affinity DataKd:  7.70E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetMAPK/MAK/MRK overlapping kinase(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 528522BDBM528522(US11192859, Compound 6)
Affinity DataKd:  9.90E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Use the plate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent