Compile Data Set for Download or QSAR
Report error Found 244 Enz. Inhib. hit(s) with all data for entry = 7096
TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173706BDBM173706(US9102591, (-)2-chloro-N-[3-[1-(trifluoromethyl)cy...)
Affinity DataIC50: 0.0900nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173649BDBM173649(US9102591, 2,3-dichloro-N-[[4,4-difluoro-1-(6-fluo...)
Affinity DataIC50: 0.280nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173675BDBM173675(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50: 0.310nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173682BDBM173682(US9102591, 2-chloro-N-((4,4-difluoro-1-(6-(trifluo...)
Affinity DataIC50: 0.540nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173675BDBM173675(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50: 0.550nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173681BDBM173681(US9102591, 3-bromo-N-((4,4-difluoro-1-(6-(trifluor...)
Affinity DataIC50: 0.710nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173739BDBM173739(US9102591, (-)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50: 0.710nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173651BDBM173651(US9102591, 2-chloro-N-[[4,4-difluoro-1-(6-fluoro-3...)
Affinity DataIC50: 0.760nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173694BDBM173694(US9102591, 2,3-dichloro-N-[2-(6-cyclopropyl-3-pyri...)
Affinity DataIC50: 0.760nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173753BDBM173753(US9102591, (-)2,6-dichloro-N-[3-cyclopropyl-2-[2-(...)
Affinity DataIC50: 0.820nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173661BDBM173661(US9102591, 2-chloro-N-((4,4-difluoro-1-(6-fluoropy...)
Affinity DataIC50: 0.830nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173710BDBM173710(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2-[2-(...)
Affinity DataIC50: 0.860nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173710BDBM173710(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2-[2-(...)
Affinity DataIC50: 0.880nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173739BDBM173739(US9102591, (-)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50: 0.890nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173775BDBM173775(US9102591, 2,3-dichloro-N-[[4,4-difluoro-1-[2-(tri...)
Affinity DataIC50: 0.950nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173668BDBM173668(US9102591, 2,3-dichloro-N-((4,4-difluoro-1-(6-meth...)
Affinity DataIC50: 0.960nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173643BDBM173643(US9102591, 2,3-Dichloro-N-[4-methyl-2-(6-methyl-py...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173826BDBM173826(US9102591, (-)2,3-dichloro-N-[2-(4-fluorophenyl)-2...)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173652BDBM173652(US9102591, 2-chloro-N-[[4,4-difluoro-1-(6-fluoro-3...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173739BDBM173739(US9102591, (-)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173665BDBM173665(US9102591, 2,3-dichloro-N-((4,4-difluoro-1-(6-(tri...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173826BDBM173826(US9102591, (-)2,3-dichloro-N-[2-(4-fluorophenyl)-2...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173674BDBM173674(US9102591, 2,3-dichloro-N-((4,4-difluoro-1-(5-fluo...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173667BDBM173667(US9102591, 2,3-dichloro-N-((1-(6-cyclopropylpyridi...)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173733BDBM173733(US9102591, 2-chloro-N-((4,4-difluoro-1-(6-(trifluo...)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173761BDBM173761(US9102591, (+)N-[3-cyclopropyl-2-[2-(trifluorometh...)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173687BDBM173687(US9102591, (+)2,3-dichloro-N-[2-(2-methylpyrimidin...)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173796BDBM173796(US9102591, (-)2,3-dichloro-N-[3-[1-(trifluoromethy...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173749BDBM173749(US9102591, 2,3-dichloro-N-[2-(4-chlorophenyl)-2-te...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173697BDBM173697(US9102591, 2,3-dichloro-N-[3-[1-(difluoromethyl)cy...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173678BDBM173678(US9102591, N-((4,4-difluoro-1-(6-(trifluoromethyl)...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173834BDBM173834(US9102591, (-)2-chloro-3-fluoro-N-[2-(4-fluorophen...)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173853BDBM173853(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2]benz...)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173848BDBM173848(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2-[2-(...)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173828BDBM173828(US9102591, (-)2-chloro-N-[2-(4-fluorophenyl)-2-[2-...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173730BDBM173730(US9102591, 2-chloro-N-((4,4-difluoro-1-(6-(trifluo...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173715BDBM173715(US9102591, (-)2-chloro-N-[3-cyclopropyl-2-[6-(trif...)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173706BDBM173706(US9102591, (-)2-chloro-N-[3-[1-(trifluoromethyl)cy...)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173820BDBM173820(US9102591, (-)2-chloro-N-[2-(4-fluorophenyl)-2-[6-...)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173660BDBM173660(US9102591, 2,5-dichloro-N-((4,4-difluoro-1-(6-fluo...)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173676BDBM173676(US9102591, (-)2-chloro-N-[3-cyclopropyl-2-[6-(trif...)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173639BDBM173639(US9102591, 2-Chloro-5-methyl-N-(1-methyl-4-phenyl-...)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173785BDBM173785(US9102591, (+)2-chloro-N-[3-[1-(trifluoromethyl)cy...)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173671BDBM173671(US9102591, N-((4,4-difluoro-1-(6-(trifluoromethyl)...)
Affinity DataIC50: 2.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173832BDBM173832(US9102591, (-)2-chloro-6-fluoro-N-[2-(4-fluorophen...)
Affinity DataIC50: 2.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173675BDBM173675(US9102591, (-)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50: 2.60nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173724BDBM173724(US9102591, 2(-)-chloro-N-[3-cyclopropyl-2-[6-(trif...)
Affinity DataIC50: 2.90nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173820BDBM173820(US9102591, (-)2-chloro-N-[2-(4-fluorophenyl)-2-[6-...)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173735BDBM173735(US9102591, 3-chloro-N-((4,4-difluoro-1-(6-(trifluo...)
Affinity DataIC50: 3.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 173744BDBM173744(US9102591, (-)2-chloro-N-[3-cyclopropyl-2-[2-(trif...)
Affinity DataIC50: 3.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

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