Report error Found 110 Enz. Inhib. hit(s) with all data for entry = 7909
Affinity DataKd: 140nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 170nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKi: 260nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 370nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 390nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 390nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 420nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 450nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 510nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 520nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 850nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 980nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.20E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.20E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.30E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.35E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.37E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.45E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.62E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.70E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 1.74E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.74E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.79E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 1.99E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 2.20E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKi: 2.40E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKi: 2.40E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 2.40E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 2.40E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 2.60E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 3.00E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 3.08E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [409-556](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 3.57E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 3.66E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 4.07E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 4.58E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 4.60E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 5.25E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 6.03E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 6.27E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKi: 6.70E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKi: 6.90E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 7.59E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 7.76E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 7.90E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
